Gene detail

IIC_RS15345

Histidine kinase, Classic

Bacillus cereus VD021 · GCF_000399145

ClassHKTypeClassicLength472 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000399145#IIC_RS15345Stable P2CS identifier used across views.
GenomeGCF_000399145Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1696912Run 6 · 4 sequences · id 100% · cov 80% · representative
External referencesWP_016101886.1 · R8HN75 · MIST4 IIC_RS15345RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length472 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 472 aa (52.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa472 aa
HAMP: 171-241 aa (71 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 362-470 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
171-241 aa · 71 aa · 15.0% of protein
Raw tokenHAMP:171:0.000000000381:241:71:69
2 HisKA#2
245-312 aa · 68 aa · 14.4% of protein
Raw tokenHisKA:245:1.82e-16:312:68:64
3 HATPase_c#3
362-470 aa · 109 aa · 23.1% of protein
Raw tokenHATPase_c:362:2.84e-28:470:109:109
  • Raw architecture: HAMP:171:0.000000000381:241:71:69#HisKA:245:1.82e-16:312:68:64#HATPase_c:362:2.84e-28:470:109:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000399145::NZ_KB976280.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18659-20748Genomic interval covered by the local TCS group.
Identifiers
Old locus tagIIC_02936RefSeq proteinWP_016101886.1
Context group IDGCF_000399145::NZ_KB976280.1::G00036
Context members
IIC_RS15340IIC_RS15345
Partner locus tags
IIC_RS15340IIC_RS15345
Partner old locus tags
IIC_02935IIC_02936
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_016101886.1Primary protein accession used for annex mappings.
UniProt accessionR8HN75Primary UniProt accession resolved in the annex database.
UniProt IDR8HN75_BACCEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagIIC_RS15345Primary locus identifier stored in the genes table.
Old locus tagIIC_02936Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB976280.1Sequence record reported by the local genomic context database.
Genomic interval19 330-20 748 nt1 419 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 659-20 748 ntGCF_000399145::NZ_KB976280.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000399145::NZ_KB976280.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB976280.1All displayed genes belong to this local TCS context.
Neighborhood span18 659-20 748 nt2 090 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 659 nt20 748 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

IIC_RS15340GCF_000399145#IIC_RS15340
RROmpR

18 659-19 333 nt · Forward (+)

Old locus IIC_02935RefSeq WP_002032425.1
IIC_RS15345GCF_000399145#IIC_RS15345
HKClassicCurrent focus

19 330-20 748 nt · Forward (+)

Old locus IIC_02936RefSeq WP_016101886.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1696912Run 6 · HK · 4 sequences
Representative sequenceGCF_000399145#IIC_RS15345The current gene is the representative for this cluster.
PFAM architectureArlS_N + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1696912

Simplified PFAM architecture for HKOC_1696912

PFAM domain coverage: 353 / 472 aa (74.8%)

1 aa472 aa
ArlS_N: 42-165 aaArlS_NHAMP: 188-240 aaHAMPHisKA: 246-312 aaHisKAHATPase_c: 361-469 aaHATPase_c
ArlS_NHAMPHisKAHATPase_c
  • Simplified architecture: ArlS_N + HAMP + HisKA + HATPase_c
  • Raw architecture: ArlS_N[42-165] | HAMP[188-240] | HisKA[246-312] | HATPase_c[361-469]
  • Domain count: 4
  • Matched identifier: HKOC_1696912
  • Positioned domains: ArlS_N 42-165 ; HAMP 188-240 ; HisKA 246-312 ; HATPase_c 361-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000399145#IIC_RS15345

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 224 · GCF_000399145
AssemblyBaci_cere_VD021_V1 · Scaffoldhaploid
Genome composition6 097 836 bp · 35,0% GCBacillus cereus VD021
Signal transduction countsGenes 121 · HK 65 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key