Gene detail

HMPREF1093_RS00625

Histidine kinase, Classic

Hungatella hathewayi 12489931 · GCF_000371445

ClassHKTypeClassicLength445 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000371445#HMPREF1093_RS00625Stable P2CS identifier used across views.
GenomeGCF_000371445Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Hungatella
Selected clusterHKOC_1043332Run 6 · 6 sequences · id 100% · cov 80%
External referencesWP_198292938.1 · MIST4 HMPREF1093_RS00625RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HAMPHis_kinaseHATPase_c
Protein length445 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage360 / 445 aa (80.9%)Merged over positioned domains only.
Domain description1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF1093_RS00625
Domain-by-domain annotation4 items
1 dCache_1#1
13-106 aa · 94 aa · 21.1% of protein
Raw tokendCache_1:13:0.0000261:106:109:195
2 HAMP#2
125-195 aa · 71 aa · 16.0% of protein
Raw tokenHAMP:125:0.0000000000522:195:71:69
3 His_kinase#3
210-288 aa · 79 aa · 17.8% of protein
Raw tokenHis_kinase:210:5.33e-27:288:80:80
4 HATPase_c#4
304-419 aa · 116 aa · 26.1% of protein
Raw tokenHATPase_c:304:0.00000000000125:419:122:109
  • Raw architecture: dCache_1:13:0.0000261:106:109:195#HAMP:125:0.0000000000522:195:71:69#His_kinase:210:5.33e-27:288:80:80#HATPase_c:304:0.00000000000125:419:122:109
  • Domain description: 1 dCache_1,1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000371445::NZ_KB850950.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span141085-143866Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1093_00120RefSeq proteinWP_198292938.1
Context group IDGCF_000371445::NZ_KB850950.1::G00005
Context members
HMPREF1093_RS00620HMPREF1093_RS00625
Partner locus tags
HMPREF1093_RS00620HMPREF1093_RS00625
Partner old locus tags
HMPREF1093_00119HMPREF1093_00120
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_198292938.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1093_RS00625Primary locus identifier stored in the genes table.
Old locus tagHMPREF1093_00120Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB850950.1Sequence record reported by the local genomic context database.
Genomic interval142 529-143 866 nt1 338 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span141 085-143 866 ntGCF_000371445::NZ_KB850950.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000371445::NZ_KB850950.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB850950.1All displayed genes belong to this local TCS context.
Neighborhood span141 085-143 866 nt2 782 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
141 085 nt143 866 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1093_RS00620GCF_000371445#HMPREF1093_RS00620
RRunclassified

141 085-142 557 nt · Reverse (-)

Old locus HMPREF1093_00119RefSeq WP_002599933.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1043332Run 6 · HK · 6 sequences
Representative sequenceGCF_003435045#DWX31_RS21315Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1043332

Simplified PFAM architecture for HKOC_1043332

PFAM domain coverage: 235 / 602 aa (39.0%)

1 aa602 aa
HAMP: 310-351 aaHAMPHis_kinase: 367-445 aaHis_kinaseHATPase_c: 461-574 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[310-351] | His_kinase[367-445] | HATPase_c[461-574]
  • Domain count: 3
  • Matched identifier: HKOC_1043332
  • Positioned domains: HAMP 310-351 ; His_kinase 367-445 ; HATPase_c 461-574
Cluster members and taxonomy
Visualization

Representative gene: GCF_003435045#DWX31_RS21315

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 999 412 · GCF_000371445
AssemblyClos_hath_12489931_V1 · Scaffoldhaploid
Genome composition6 873 024 bp · 49,5% GCHungatella hathewayi 12489931
Signal transduction countsGenes 266 · HK 130 · RR 132CheA 1 · PP 4
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusHungatella
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Hungatella

Related genes

Preview from the same derived genome key