1 HisKA#1
268-336 aa · 69 aa · 14.1% of protein
Raw token
HisKA:268:0.00000000000000964:336:69:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC180050_RS00520
Histidine kinase, Classic
Escherichia coli 180050 · GCF_000356045
ClassHKTypeClassicLength490 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000356045#EC180050_RS00520Stable P2CS identifier used across views.
GenomeGCF_000356045Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length490 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage178 / 490 aa (36.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa490 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
382-490 aa · 109 aa · 22.2% of protein
Raw token
HATPase_c:382:1.19e-25:490:111:109- Raw architecture: HisKA:268:0.00000000000000964:336:69:64#HATPase_c:382:1.19e-25:490:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000356045::NZ_AQEH01000033.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1477-3668Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEC180050_4950RefSeq proteinWP_001741109.1
Context group ID
GCF_000356045::NZ_AQEH01000033.1::G00001Context members
EC180050_RS00520EC180050_RS00525
Partner locus tags
EC180050_RS00520EC180050_RS00525
Partner old locus tags
EC180050_4950EC180050_4951
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_001741109.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC180050_RS00520Primary locus identifier stored in the genes table.
Old locus tagEC180050_4950Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AQEH01000033.1Sequence record reported by the local genomic context database.
Genomic interval1 477-2 949 nt1 473 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 477-3 668 ntGCF_000356045::NZ_AQEH01000033.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000356045::NZ_AQEH01000033.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQEH01000033.1All displayed genes belong to this local TCS context.
Neighborhood span1 477-3 668 nt2 192 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 477 nt3 668 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EC180050_RS00520GCF_000356045#EC180050_RS00520
HKClassicCurrent focus
1 477-2 949 nt · Reverse (-)
EC180050_RS00525GCF_000356045#EC180050_RS00525
RROmpR
2 946-3 668 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000356045#EC180050_RS00520The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1533900
Simplified PFAM architecture for HKOC_1533900
PFAM domain coverage: 177 / 490 aa (36.1%)
1 aa490 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[268-336] | HATPase_c[383-490]
- Domain count: 2
- Matched identifier: HKOC_1533900
- Positioned domains: HisKA 268-336 ; HATPase_c 383-490
Cluster members and taxonomy
Representative gene: GCF_000356045#EC180050_RS00520
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 116 103 · GCF_000356045
AssemblyASM35604v2 · Contighaploid
Genome composition4 808 558 bp · 50,5% GCEscherichia coli 180050
Signal transduction countsGenes 64 · HK 31 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key