Gene detail

ECK5_RS00255

Histidine kinase, Classic

Escherichia coli O10:K5(L):H4 str. ATCC 23506 · GCF_000333175

ClassHKTypeClassicLength493 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000333175#ECK5_RS00255Stable P2CS identifier used across views.
GenomeGCF_000333175Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1514832Run 6 · 4260 sequences · id 100% · cov 80%
External referencesWP_000555736.1 · A0A7W3EKN3 · MIST4 ECK5_RS00255RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length493 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 493 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa493 aa
HAMP: 188-258 aa (71 aa)1HisKA: 262-328 aa (67 aa)2HATPase_c: 372-480 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
188-258 aa · 71 aa · 14.4% of protein
Raw tokenHAMP:188:0.000000000461:258:71:69
2 HisKA#2
262-328 aa · 67 aa · 13.6% of protein
Raw tokenHisKA:262:0.00000000000597:328:67:64
3 HATPase_c#3
372-480 aa · 109 aa · 22.1% of protein
Raw tokenHATPase_c:372:6.46e-29:480:110:109
  • Raw architecture: HAMP:188:0.000000000461:258:71:69#HisKA:262:0.00000000000597:328:67:64#HATPase_c:372:6.46e-29:480:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000333175::NZ_CAPK01000220.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span29378-31532Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECK5_50750RefSeq proteinWP_000555736.1
Context group IDGCF_000333175::NZ_CAPK01000220.1::G00001
Context members
ECK5_RS00255ECK5_RS00250
Partner locus tags
ECK5_RS00255ECK5_RS00250
Partner old locus tags
ECK5_50750ECK5_50760
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000555736.1Primary protein accession used for annex mappings.
UniProt accessionA0A7W3EKN3Primary UniProt accession resolved in the annex database.
UniProt IDA0A7W3EKN3_ESCFEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECK5_RS00255Primary locus identifier stored in the genes table.
Old locus tagECK5_50750Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAPK01000220.1Sequence record reported by the local genomic context database.
Genomic interval29 378-30 859 nt1 482 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span29 378-31 532 ntGCF_000333175::NZ_CAPK01000220.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000333175::NZ_CAPK01000220.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAPK01000220.1All displayed genes belong to this local TCS context.
Neighborhood span29 378-31 532 nt2 155 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 378 nt31 532 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECK5_RS00255GCF_000333175#ECK5_RS00255
HKClassicCurrent focus

29 378-30 859 nt · Reverse (-)

Old locus ECK5_50750RefSeq WP_000555736.1
ECK5_RS00250GCF_000333175#ECK5_RS00250
RROmpR

30 852-31 532 nt · Reverse (-)

Old locus ECK5_50760RefSeq WP_000697968.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1514832Run 6 · HK · 4260 sequences
Representative sequenceGCF_000014845#APECO1_RS27245Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1514832

Simplified PFAM architecture for HKOC_1514832

PFAM domain coverage: 399 / 493 aa (80.9%)

1 aa493 aa
CusS: 8-181 aaCusSHAMP: 208-257 aaHAMPHisKA: 263-327 aaHisKAHATPase_c: 372-481 aaHATPase_c
CusSHAMPHisKAHATPase_c
  • Simplified architecture: CusS + HAMP + HisKA + HATPase_c
  • Raw architecture: CusS[8-181] | HAMP[208-257] | HisKA[263-327] | HATPase_c[372-481]
  • Domain count: 4
  • Matched identifier: HKOC_1514832
  • Positioned domains: CusS 8-181 ; HAMP 208-257 ; HisKA 263-327 ; HATPase_c 372-481
Cluster members and taxonomy
Visualization

Representative gene: GCF_000014845#APECO1_RS27245

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 246 623 · GCF_000333175
AssemblyASM33317v1 · Contighaploid
Genome composition5 095 957 bp · 50,5% GCEscherichia coli O10:K5(L):H4 str. ATCC 23506
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key