1 HAMP#1
188-258 aa · 71 aa · 14.4% of protein
Raw token
HAMP:188:0.000000000461:258:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
APECO1_RS27245
Histidine kinase, Classic
Escherichia coli APEC O1 · GCF_000014845
ClassHKTypeClassicLength493 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000014845#APECO1_RS27245Stable P2CS identifier used across views.
GenomeGCF_000014845Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length493 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage247 / 493 aa (50.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa493 aa
Domain-by-domain annotation3 items
2 HisKA#2
262-328 aa · 67 aa · 13.6% of protein
Raw token
HisKA:262:0.00000000000597:328:67:643 HATPase_c#3
372-480 aa · 109 aa · 22.1% of protein
Raw token
HATPase_c:372:6.46e-29:480:110:109- Raw architecture: HAMP:188:0.000000000461:258:71:69#HisKA:262:0.00000000000597:328:67:64#HATPase_c:372:6.46e-29:480:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000014845::NC_009838.1::G00040
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span121550-123704Genomic interval covered by the local TCS group.
Identifiers
Old locus tagAPECO1_O1R109%2CO1R_109RefSeq proteinWP_000555736.1
Context group ID
GCF_000014845::NC_009838.1::G00040Context members
APECO1_RS27245APECO1_RS27250
Partner locus tags
APECO1_RS27245APECO1_RS27250
Partner old locus tags
APECO1_O1R109%2CO1R_109APECO1_O1R110%2CO1R_110
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000555736.1Primary protein accession used for annex mappings.
UniProt accessionA0A7W3EKN3Primary UniProt accession resolved in the annex database.
UniProt IDA0A7W3EKN3_ESCFEDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAPECO1_RS27245Primary locus identifier stored in the genes table.
Old locus tagAPECO1_O1R109%2CO1R_109Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_009838.1Sequence record reported by the local genomic context database.
Genomic interval121 550-123 031 nt1 482 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span121 550-123 704 ntGCF_000014845::NC_009838.1::G00040
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000014845::NC_009838.1::G00040Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_009838.1All displayed genes belong to this local TCS context.
Neighborhood span121 550-123 704 nt2 155 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
121 550 nt123 704 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
APECO1_RS27245GCF_000014845#APECO1_RS27245
HKClassicCurrent focus
121 550-123 031 nt · Reverse (-)
APECO1_RS27250GCF_000014845#APECO1_RS27250
RROmpR
123 024-123 704 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000014845#APECO1_RS27245The current gene is the representative for this cluster.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1514832
Simplified PFAM architecture for HKOC_1514832
PFAM domain coverage: 399 / 493 aa (80.9%)
1 aa493 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-181] | HAMP[208-257] | HisKA[263-327] | HATPase_c[372-481]
- Domain count: 4
- Matched identifier: HKOC_1514832
- Positioned domains: CusS 8-181 ; HAMP 208-257 ; HisKA 263-327 ; HATPase_c 372-481
Cluster members and taxonomy
Representative gene: GCF_000014845#APECO1_RS27245
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 405 955 · GCF_000014845
AssemblyASM1484v1 · Complete Genomehaploid
Genome composition5 497 653 bp · 50,5% GCEscherichia coli APEC O1
Signal transduction countsGenes 70 · HK 34 · RR 36CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key