Gene detail

WGQ_RS12040

Histidine kinase, Classic

Escherichia coli KTE232 · GCF_000326825

ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000326825#WGQ_RS12040Stable P2CS identifier used across views.
GenomeGCF_000326825Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1937412Run 6 · 400 sequences · id 100% · cov 80% · representative
External referencesWP_001543853.1 · A0A2X6D7U1 · MIST4 WGQ_RS12040RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 452 aa (53.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
HAMP: 161-229 aa (69 aa)1HisKA: 235-299 aa (65 aa)2HATPase_c: 344-452 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
161-229 aa · 69 aa · 15.3% of protein
Raw tokenHAMP:161:0.000000000871:229:69:69
2 HisKA#2
235-299 aa · 65 aa · 14.4% of protein
Raw tokenHisKA:235:0.0000000000807:299:65:64
3 HATPase_c#3
344-452 aa · 109 aa · 24.1% of protein
Raw tokenHATPase_c:344:4.03e-17:452:113:109
  • Raw architecture: HAMP:161:0.000000000871:229:69:69#HisKA:235:0.0000000000807:299:65:64#HATPase_c:344:4.03e-17:452:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000326825::NZ_ANYS01000041.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span156016-158045Genomic interval covered by the local TCS group.
Identifiers
Old locus tagWGQ_02085RefSeq proteinWP_001543853.1
Context group IDGCF_000326825::NZ_ANYS01000041.1::G00017
Context members
WGQ_RS12040WGQ_RS12035
Partner locus tags
WGQ_RS12040WGQ_RS12035
Partner old locus tags
WGQ_02085WGQ_02086
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001543853.1Primary protein accession used for annex mappings.
UniProt accessionA0A2X6D7U1Primary UniProt accession resolved in the annex database.
UniProt IDA0A2X6D7U1_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagWGQ_RS12040Primary locus identifier stored in the genes table.
Old locus tagWGQ_02085Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ANYS01000041.1Sequence record reported by the local genomic context database.
Genomic interval156 016-157 374 nt1 359 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span156 016-158 045 ntGCF_000326825::NZ_ANYS01000041.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000326825::NZ_ANYS01000041.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ANYS01000041.1All displayed genes belong to this local TCS context.
Neighborhood span156 016-158 045 nt2 030 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
156 016 nt158 045 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

WGQ_RS12040GCF_000326825#WGQ_RS12040
HKClassicCurrent focus

156 016-157 374 nt · Reverse (-)

Old locus WGQ_02085RefSeq WP_001543853.1
WGQ_RS12035GCF_000326825#WGQ_RS12035
RROmpR

157 374-158 045 nt · Reverse (-)

Old locus WGQ_02086RefSeq WP_001340597.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1937412Run 6 · HK · 400 sequences
Representative sequenceGCF_000326825#WGQ_RS12040The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1937412

Simplified PFAM architecture for HKOC_1937412

PFAM domain coverage: 172 / 452 aa (38.1%)

1 aa452 aa
HisKA: 236-300 aaHisKAHATPase_c: 345-451 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[236-300] | HATPase_c[345-451]
  • Domain count: 2
  • Matched identifier: HKOC_1937412
  • Positioned domains: HisKA 236-300 ; HATPase_c 345-451
Cluster members and taxonomy
Visualization

Representative gene: GCF_000326825#WGQ_RS12040

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 365 · GCF_000326825
AssemblyEsch_coli_KTE232_V1 · Contighaploid
Genome composition4 755 075 bp · 51,0% GCEscherichia coli KTE232
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key