Gene detail

WGQ_RS02410

Histidine kinase, Classic

Escherichia coli KTE232 · GCF_000326825

ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000326825#WGQ_RS02410Stable P2CS identifier used across views.
GenomeGCF_000326825Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1873620Run 6 · 1479 sequences · id 100% · cov 80%
External referencesWP_000580424.1 · A0A403M193 · MIST4 WGQ_RS02410RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
HAMP: 165-234 aa (70 aa)1HisKA: 238-299 aa (62 aa)2HATPase_c: 345-453 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:165:0.000000000000878:234:70:69
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw tokenHisKA:238:6.91e-17:299:63:64
3 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw tokenHATPase_c:345:5.89e-30:453:110:109
  • Raw architecture: HAMP:165:0.000000000000878:234:70:69#HisKA:238:6.91e-17:299:63:64#HATPase_c:345:5.89e-30:453:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000326825::NZ_ANYS01000074.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span64197-66265Genomic interval covered by the local TCS group.
Identifiers
Old locus tagWGQ_04072RefSeq proteinWP_000580424.1
Context group IDGCF_000326825::NZ_ANYS01000074.1::G00035
Context members
WGQ_RS02410WGQ_RS02405
Partner locus tags
WGQ_RS02410WGQ_RS02405
Partner old locus tags
WGQ_04072WGQ_04073
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000580424.1Primary protein accession used for annex mappings.
UniProt accessionA0A403M193Primary UniProt accession resolved in the annex database.
UniProt IDA0A403M193_SHIDYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagWGQ_RS02410Primary locus identifier stored in the genes table.
Old locus tagWGQ_04072Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ANYS01000074.1Sequence record reported by the local genomic context database.
Genomic interval64 197-65 570 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span64 197-66 265 ntGCF_000326825::NZ_ANYS01000074.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000326825::NZ_ANYS01000074.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ANYS01000074.1All displayed genes belong to this local TCS context.
Neighborhood span64 197-66 265 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
64 197 nt66 265 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

WGQ_RS02410GCF_000326825#WGQ_RS02410
HKClassicCurrent focus

64 197-65 570 nt · Reverse (-)

Old locus WGQ_04072RefSeq WP_000580424.1
WGQ_RS02405GCF_000326825#WGQ_RS02405
RROmpR

65 567-66 265 nt · Reverse (-)

Old locus WGQ_04073RefSeq WP_001033722.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1873620Run 6 · HK · 1479 sequences
Representative sequenceGCF_000225205#BD16_RS03410Use this link to inspect the representative gene detail.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1873620

Simplified PFAM architecture for HKOC_1873620

PFAM domain coverage: 293 / 457 aa (64.1%)

1 aa457 aa
CpxA_peri: 82-150 aaCpxA_periHAMP: 181-233 aaHAMPHisKA: 239-299 aaHisKAHATPase_c: 345-454 aaHATPase_c
CpxA_periHAMPHisKAHATPase_c
  • Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
  • Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
  • Domain count: 4
  • Matched identifier: HKOC_1873620
  • Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Visualization

Representative gene: GCF_000225205#BD16_RS03410

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 365 · GCF_000326825
AssemblyEsch_coli_KTE232_V1 · Contighaploid
Genome composition4 755 075 bp · 51,0% GCEscherichia coli KTE232
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key