Gene detail

WGQ_RS10515

Histidine kinase, Classic

Escherichia coli KTE232 · GCF_000326825

ClassHKTypeClassicLength608 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000326825#WGQ_RS10515Stable P2CS identifier used across views.
GenomeGCF_000326825Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1012976Run 6 · 2987 sequences · id 100% · cov 80%
External referencesWP_000559135.1 · A0A0H4AJQ3 · MIST4 WGQ_RS10515RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length608 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage346 / 608 aa (56.9%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa608 aa
HAMP: 192-259 aa (68 aa)1PAS: 265-370 aa (106 aa)2HisKA: 389-452 aa (64 aa)3HATPase_c: 495-602 aa (108 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
192-259 aa · 68 aa · 11.2% of protein
Raw tokenHAMP:192:0.000000000953:259:69:69
2 PAS#2
265-370 aa · 106 aa · 17.4% of protein
Raw tokenPAS:265:4.23e-21:370:110:113
3 HisKA#3
389-452 aa · 64 aa · 10.5% of protein
Raw tokenHisKA:389:0.00000000000000179:452:64:64
4 HATPase_c#4
495-602 aa · 108 aa · 17.8% of protein
Raw tokenHATPase_c:495:5.5e-27:602:112:109
  • Raw architecture: HAMP:192:0.000000000953:259:69:69#PAS:265:4.23e-21:370:110:113#HisKA:389:0.00000000000000179:452:64:64#HATPase_c:495:5.5e-27:602:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000326825::NZ_ANYS01000050.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span15115-18323Genomic interval covered by the local TCS group.
Identifiers
Old locus tagWGQ_02402RefSeq proteinWP_000559135.1
Context group IDGCF_000326825::NZ_ANYS01000050.1::G00023
Context members
WGQ_RS10515WGQ_RS10510
Partner locus tags
WGQ_RS10515WGQ_RS10510
Partner old locus tags
WGQ_02402WGQ_02403
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000559135.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H4AJQ3Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H4AJQ3_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 2Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagWGQ_RS10515Primary locus identifier stored in the genes table.
Old locus tagWGQ_02402Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ANYS01000050.1Sequence record reported by the local genomic context database.
Genomic interval15 115-16 941 nt1 827 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span15 115-18 323 ntGCF_000326825::NZ_ANYS01000050.1::G00023

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000326825::NZ_ANYS01000050.1::G00023

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ANYS01000050.1All displayed genes belong to this local TCS context.
Neighborhood span15 115-18 323 nt3 209 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
15 115 nt18 323 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

WGQ_RS10515GCF_000326825#WGQ_RS10515
HKClassicCurrent focus

15 115-16 941 nt · Forward (+)

Old locus WGQ_02402RefSeq WP_000559135.1
WGQ_RS10510GCF_000326825#WGQ_RS10510
RRPrrA

16 938-18 323 nt · Forward (+)

Old locus WGQ_02403RefSeq WP_000125282.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1012976Run 6 · HK · 2987 sequences
Representative sequenceGCF_000009565#B21_RS11135Use this link to inspect the representative gene detail.
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1012976

Simplified PFAM architecture for HKOC_1012976

PFAM domain coverage: 273 / 608 aa (44.9%)

1 aa608 aa
PAS: 265-369 aaPASHisKA: 389-451 aaHisKAHATPase_c: 496-600 aaHATPase_c
PASHisKAHATPase_c
  • Simplified architecture: PAS + HisKA + HATPase_c
  • Raw architecture: PAS[265-369] | HisKA[389-451] | HATPase_c[496-600]
  • Domain count: 3
  • Matched identifier: HKOC_1012976
  • Positioned domains: PAS 265-369 ; HisKA 389-451 ; HATPase_c 496-600
Cluster members and taxonomy
Visualization

Representative gene: GCF_000009565#B21_RS11135

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 365 · GCF_000326825
AssemblyEsch_coli_KTE232_V1 · Contighaploid
Genome composition4 755 075 bp · 51,0% GCEscherichia coli KTE232
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key