1 HAMP#1
287-357 aa · 71 aa · 12.4% of protein
Raw token
HAMP:287:0.000000648:357:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
OIA_RS18095
Histidine kinase, Classic
Enterococcus faecium EnGen0018 · GCF_000321825
ClassHKTypeClassicLength574 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000321825#OIA_RS18095Stable P2CS identifier used across views.
GenomeGCF_000321825Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length574 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 574 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa574 aa
Domain-by-domain annotation3 items
2 His_kinase#2
372-450 aa · 79 aa · 13.8% of protein
Raw token
His_kinase:372:2.52e-28:450:80:803 HATPase_c#3
469-573 aa · 105 aa · 18.3% of protein
Raw token
HATPase_c:469:0.000000000182:573:108:109- Raw architecture: HAMP:287:0.000000648:357:71:69#His_kinase:372:2.52e-28:450:80:80#HATPase_c:469:0.000000000182:573:108:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000321825::NZ_KB029662.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span43579-46751Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOIA_05000RefSeq proteinWP_002285976.1
Context group ID
GCF_000321825::NZ_KB029662.1::G00019Context members
OIA_RS18090OIA_RS18095
Partner locus tags
OIA_RS18090OIA_RS18095
Partner old locus tags
OIA_04999OIA_05000
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002285976.1Primary protein accession used for annex mappings.
UniProt accessionQ3Y3H2Primary UniProt accession resolved in the annex database.
UniProt IDQ3Y3H2_ENTFDDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagOIA_RS18095Primary locus identifier stored in the genes table.
Old locus tagOIA_05000Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB029662.1Sequence record reported by the local genomic context database.
Genomic interval45 027-46 751 nt1 725 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span43 579-46 751 ntGCF_000321825::NZ_KB029662.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000321825::NZ_KB029662.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB029662.1All displayed genes belong to this local TCS context.
Neighborhood span43 579-46 751 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 579 nt46 751 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
OIA_RS18090GCF_000321825#OIA_RS18090
RRunclassified
43 579-45 030 nt · Reverse (-)
OIA_RS18095GCF_000321825#OIA_RS18095
HKClassicCurrent focus
45 027-46 751 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS13170Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1192838
Simplified PFAM architecture for HKOC_1192838
PFAM domain coverage: 224 / 574 aa (39.0%)
1 aa574 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[316-357] | His_kinase[372-449] | HATPase_c[469-572]
- Domain count: 3
- Matched identifier: HKOC_1192838
- Positioned domains: HAMP 316-357 ; His_kinase 372-449 ; HATPase_c 469-572
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS13170
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 138 899 · GCF_000321825
AssemblyEnte_faec_E1576_V1 · Scaffoldhaploid
Genome composition2 713 803 bp · 38,0% GCEnterococcus faecium EnGen0018
Signal transduction countsGenes 35 · HK 16 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key