Gene detail

OIA_RS07590

Histidine kinase, Classic

Enterococcus faecium EnGen0018 · GCF_000321825

ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000321825#OIA_RS07590Stable P2CS identifier used across views.
GenomeGCF_000321825Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1602550Run 6 · 463 sequences · id 100% · cov 80%
External referencesWP_002293941.1 · A0A829F7L6 · MIST4 OIA_RS07590RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 482 aa (50.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
HAMP: 179-244 aa (66 aa)1HisKA: 255-321 aa (67 aa)2HATPase_c: 366-475 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
179-244 aa · 66 aa · 13.7% of protein
Raw tokenHAMP:179:0.00000000000021:244:66:69
2 HisKA#2
255-321 aa · 67 aa · 13.9% of protein
Raw tokenHisKA:255:0.00000000000000161:321:67:64
3 HATPase_c#3
366-475 aa · 110 aa · 22.8% of protein
Raw tokenHATPase_c:366:6.9e-31:475:110:109
  • Raw architecture: HAMP:179:0.00000000000021:244:66:69#HisKA:255:0.00000000000000161:321:67:64#HATPase_c:366:6.9e-31:475:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000321825::NZ_KB029628.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span383981-386145Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOIA_02960RefSeq proteinWP_002293941.1
Context group IDGCF_000321825::NZ_KB029628.1::G00004
Context members
OIA_RS07585OIA_RS07590
Partner locus tags
OIA_RS07585OIA_RS07590
Partner old locus tags
OIA_02959OIA_02960
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002293941.1Primary protein accession used for annex mappings.
UniProt accessionA0A829F7L6Primary UniProt accession resolved in the annex database.
UniProt IDA0A829F7L6_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOIA_RS07590Primary locus identifier stored in the genes table.
Old locus tagOIA_02960Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB029628.1Sequence record reported by the local genomic context database.
Genomic interval384 697-386 145 nt1 449 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span383 981-386 145 ntGCF_000321825::NZ_KB029628.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000321825::NZ_KB029628.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB029628.1All displayed genes belong to this local TCS context.
Neighborhood span383 981-386 145 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
383 981 nt386 145 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OIA_RS07585GCF_000321825#OIA_RS07585
RROmpR

383 981-384 697 nt · Forward (+)

Old locus OIA_02959RefSeq WP_002293942.1
OIA_RS07590GCF_000321825#OIA_RS07590
HKClassicCurrent focus

384 697-386 145 nt · Forward (+)

Old locus OIA_02960RefSeq WP_002293941.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1602550Run 6 · HK · 463 sequences
Representative sequenceGCF_000172655#EFME1071_RS04865Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1602550

Simplified PFAM architecture for HKOC_1602550

PFAM domain coverage: 226 / 482 aa (46.9%)

1 aa482 aa
HAMP: 194-244 aaHAMPHisKA: 256-320 aaHisKAHATPase_c: 367-476 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[194-244] | HisKA[256-320] | HATPase_c[367-476]
  • Domain count: 3
  • Matched identifier: HKOC_1602550
  • Positioned domains: HAMP 194-244 ; HisKA 256-320 ; HATPase_c 367-476
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172655#EFME1071_RS04865

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 138 899 · GCF_000321825
AssemblyEnte_faec_E1576_V1 · Scaffoldhaploid
Genome composition2 713 803 bp · 38,0% GCEnterococcus faecium EnGen0018
Signal transduction countsGenes 35 · HK 16 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key