Gene detail

HMPREF0273_RS0111760

Histidine kinase, Hybrid

Coprobacillus cateniformis · GCF_000269565

ClassHKTypeHybridLength908 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000269565#HMPREF0273_RS0111760Stable P2CS identifier used across views.
GenomeGCF_000269565Bacteria; Bacillati; Bacillota; Erysipelotrichia; Erysipelotrichales; Coprobacillaceae; Coprobacillus
Selected clusterHKOC_0393767Run 6 · 5 sequences · id 100% · cov 80%
External referencesWP_008789293.1 · E7GBQ2 · MIST4 HMPREF0273_RS0111760RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_9HisKAHATPase_cResponse_reg
Protein length908 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage612 / 908 aa (67.4%)Merged over positioned domains only.
Domain description2 PAS_9,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa908 aa
PAS_9: 23-118 aa (96 aa)1PAS_9: 277-373 aa (97 aa)2HisKA: 398-464 aa (67 aa)3HATPase_c: 511-628 aa (118 aa)4Response_reg: 645-760 aa (116 aa)5Response_reg: 788-905 aa (118 aa)6
Domain-by-domain annotation6 items
1 PAS_9#1
23-118 aa · 96 aa · 10.6% of protein
Raw tokenPAS_9:23:0.000000101:118:98:102
2 PAS_9#2
277-373 aa · 97 aa · 10.7% of protein
Raw tokenPAS_9:277:0.000000296:373:97:102
3 HisKA#3
398-464 aa · 67 aa · 7.4% of protein
Raw tokenHisKA:398:1.68e-16:464:67:64
4 HATPase_c#4
511-628 aa · 118 aa · 13.0% of protein
Raw tokenHATPase_c:511:6.44e-31:628:118:109
5 Response_reg#5
645-760 aa · 116 aa · 12.8% of protein
Raw tokenResponse_reg:645:5.24e-23:760:116:111
6 Response_reg#6
788-905 aa · 118 aa · 13.0% of protein
Raw tokenResponse_reg:788:9.85e-29:905:118:111
  • Raw architecture: PAS_9:23:0.000000101:118:98:102#PAS_9:277:0.000000296:373:97:102#HisKA:398:1.68e-16:464:67:64#HATPase_c:511:6.44e-31:628:118:109#Response_reg:645:5.24e-23:760:116:111#Response_reg:788:9.85e-29:905:118:111
  • Domain description: 2 PAS_9,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000269565::NZ_AKCB01000001.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2335560-2340709Genomic interval covered by the local TCS group.
Context group IDGCF_000269565::NZ_AKCB01000001.1::G00027
Context members
HMPREF0273_RS0111760HMPREF0273_RS0111770
Partner locus tags
HMPREF0273_RS0111760HMPREF0273_RS0111770
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_008789293.1Primary protein accession used for annex mappings.
UniProt accessionE7GBQ2Primary UniProt accession resolved in the annex database.
UniProt IDE7GBQ2_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0273_RS0111760Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AKCB01000001.1Sequence record reported by the local genomic context database.
Genomic interval2 335 560-2 338 286 nt2 727 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 335 560-2 340 709 ntGCF_000269565::NZ_AKCB01000001.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000269565::NZ_AKCB01000001.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AKCB01000001.1All displayed genes belong to this local TCS context.
Neighborhood span2 335 560-2 340 709 nt5 150 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 335 560 nt2 340 709 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0393767Run 6 · HK · 5 sequences
Representative sequenceGCF_000186525#HMPREF9488_RS10980Use this link to inspect the representative gene detail.
PFAM architecturePAS_9 + PAS_9 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg7 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0393767

Simplified PFAM architecture for HKOC_0393767

PFAM domain coverage: 648 / 908 aa (71.4%)

1 aa908 aa
PAS_9: 24-118 aaPAS_9PAS_9: 153-219 aaPAS_9PAS_3: 280-349 aaPAS_3HisKA: 398-464 aaHisKAHATPase_c: 512-628 aaHATPase_cResponse_reg: 645-759 aaResponse_regResponse_reg: 788-904 aaResponse_reg
PAS_9PAS_9PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_9 + PAS_9 + PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_9[24-118] | PAS_9[153-219] | PAS_3[280-349] | HisKA[398-464] | HATPase_c[512-628] | Response_reg[645-759] | Response_reg[788-904]
  • Domain count: 7
  • Matched identifier: HKOC_0393767
  • Positioned domains: PAS_9 24-118 ; PAS_9 153-219 ; PAS_3 280-349 ; HisKA 398-464 ; HATPase_c 512-628 ; Response_reg 645-759 ; Response_reg 788-904
Cluster members and taxonomy
Visualization

Representative gene: GCF_000186525#HMPREF9488_RS10980

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 100 884 · GCF_000269565
AssemblyPB_Copr_sp_D6_V1 · Contigreference genome · haploid
Genome composition3 861 289 bp · 31,5% GCCoprobacillus cateniformis
Signal transduction countsGenes 69 · HK 31 · RR 36CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassErysipelotrichiaOrderErysipelotrichalesFamilyCoprobacillaceaeGenusCoprobacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Erysipelotrichia5Erysipelotrichales6Coprobacillaceae7Coprobacillus

Related genes

Preview from the same derived genome key