Gene detail

EC5761_RS19965

Histidine kinase, Unorthodox

Escherichia coli 576-1 · GCF_000264135

Open genome Open selected cluster RefSeq UniProt

ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired

Gene IDGCF_000264135#EC5761_RS19965Stable P2CS identifier used across views.

GenomeGCF_000264135Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia

Selected clusterHKOC_0161023Run 6 · 823 sequences · id 100% · cov 80%

External referencesWP_001323380.1 · B7N5X0 · MIST4 EC5761_RS19965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_regHpt

Protein length1197 aaLength used to scale native and Biotite-like views.

Annotated domains66 with usable coordinates.

Domain coverage796 / 1197 aa (66.5%)Merged over positioned domains only.

Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.

Signal peptideUnavailableNo TMPRED prediction file matched this gene.

Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.

Complete domain annotations

Domain view

Native Biotite-like

Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.

1 aa1197 aa

Domain-by-domain annotation6 items

1 PBPb#1

73-276 aa · 204 aa · 17.0% of protein

Raw tokenPBPb:73:4.91e-16:276:209:219

2 PBPb#2

304-519 aa · 216 aa · 18.0% of protein

Raw tokenPBPb:304:3.15e-39:519:223:219

3 HisKA#3

711-777 aa · 67 aa · 5.6% of protein

Raw tokenHisKA:711:2.5e-16:777:67:64

4 HATPase_c#4

825-938 aa · 114 aa · 9.5% of protein

Raw tokenHATPase_c:825:5.05e-32:938:114:109

5 Response_reg#5

961-1070 aa · 110 aa · 9.2% of protein

Raw tokenResponse_reg:961:2.34e-39:1070:110:111

6 Hpt#6

1104-1188 aa · 85 aa · 7.1% of protein

Raw tokenHpt:1104:0.000000366:1188:85:84

Raw architecture: PBPb:73:4.91e-16:276:209:219#PBPb:304:3.15e-39:519:223:219#HisKA:711:2.5e-16:777:67:64#HATPase_c:825:5.05e-32:938:114:109#Response_reg:961:2.34e-39:1070:110:111#Hpt:1104:0.000000366:1188:85:84
Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
TM description: N/A
TMPRED source: No TMPRED file loaded
TMPRED segments: N/A
Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000264135::NZ_AJWS01000101.1::G00015

Group size22 locus tags listed below.

HK / RR1 / 1Counts resolved for the local TCS neighborhood.

Context span1214-5426Genomic interval covered by the local TCS group.

Identifiers

Old locus tagEC5761_05454RefSeq proteinWP_001323380.1

Context group IDGCF_000264135::NZ_AJWS01000101.1::G00015

Context members

EC5761_RS19970EC5761_RS19965

Partner locus tags

EC5761_RS19970EC5761_RS19965

Partner old locus tags

EC5761_05449EC5761_05454

Partner protein IDs

WP_000991370.1 WP_001323380.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001323380.1Primary protein accession used for annex mappings.

UniProt accessionB7N5X0Primary UniProt accession resolved in the annex database.

UniProt IDB7N5X0_ECOLUDisplay identifier provided by UniProt.

GO / PubMed4 / 1Unique GO terms and literature references available below.

Reference hubs

Open RefSeq Open UniProt accession

GO terms

GO:0005886 GO:0005524 GO:0009927 GO:0000155

PubMed

19165319

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEC5761_RS19965Primary locus identifier stored in the genes table.

Old locus tagEC5761_05454Legacy locus tag recovered from the local context mapping.

Contig / repliconNZ_AJWS01000101.1Sequence record reported by the local genomic context database.

Genomic interval1 833-5 426 nt3 594 nt · Forward (+)

StrandForward (+)Strand sign follows the local context database convention.

Local TCS group span1 214-5 426 ntGCF_000264135::NZ_AJWS01000101.1::G00015

Quick actions

Open genome Search genes in genome

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000264135::NZ_AJWS01000101.1::G00015

Graphic view

Compact Biotite-like

Zoom

Full window Focus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.

Contig / repliconNZ_AJWS01000101.1All displayed genes belong to this local TCS context.

Neighborhood span1 214-5 426 nt4 213 nt

Members21 current focus gene

Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.

1 214 nt5 426 nt

+-EC5761_RS19970 EC5761_RS19965

Neighborhood gene cards

2 genes in the current local neighborhood.

EC5761_RS19970GCF_000264135#EC5761_RS19970

RRunclassified

1 214-1 828 nt · Forward (+)

Old locus EC5761_05449RefSeq WP_000991370.1

Open gene

EC5761_RS19965GCF_000264135#EC5761_RS19965

HKUnorthodoxCurrent focus

1 833-5 426 nt · Forward (+)

Old locus EC5761_05454RefSeq WP_001323380.1

Open current gene

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster

HKOC_0161023HK

Run 6823 sequencesid 100%cov 80%

PFAM SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg

Representative GCF_000026325#ECUMN_RS14455

Selected clusterHKOC_0161023Run 6 · HK · 823 sequences

Representative sequenceGCF_000026325#ECUMN_RS14455Use this link to inspect the representative gene detail.

PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg5 domains in the representative PFAM annotation.

Open in cluster search Open representative gene

PFAM architecture for HKOC_0161023

Simplified PFAM architecture for HKOC_0161023

PFAM domain coverage: 719 / 1197 aa (60.1%)

1 aa1197 aa

SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_reg

Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg
Raw architecture: SBP_bac_3[63-276] | SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070]
Domain count: 5
Matched identifier: HKOC_0161023
Positioned domains: SBP_bac_3 63-276 ; SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070

Cluster members and taxonomy

Representative gene: GCF_000026325#ECUMN_RS14455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 752 787 · GCF_000264135

AssemblyASM26413v1 · Contighaploid

Genome composition5 191 076 bp · 50,5% GCEscherichia coli 576-1

Signal transduction countsGenes 61 · HK 29 · RR 32CheA 1 · PP 0

Ranked taxonomy7 ranked levels available

SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia

Lineage path7 lineage nodes

1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Open genome Search genes in genome Search HK genes NCBI assembly files

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Preview from the same derived genome key