1 HisKA_3#1
155-224 aa · 70 aa · 19.7% of protein
Raw token
HisKA_3:155:7.01e-21:224:70:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4452_RS10065
Histidine kinase, Classic
Enterococcus faecium E4452 · GCF_000239115
ClassHKTypeClassicLength355 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239115#EFME4452_RS10065Stable P2CS identifier used across views.
GenomeGCF_000239115Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length355 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage160 / 355 aa (45.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa355 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
262-351 aa · 90 aa · 25.4% of protein
Raw token
HATPase_c:262:1.38e-18:351:105:109- Raw architecture: HisKA_3:155:7.01e-21:224:70:68#HATPase_c:262:1.38e-18:351:105:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239115::NZ_AEOU01000121.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5789-7495Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4452_2312RefSeq proteinWP_002326482.1
Context group ID
GCF_000239115::NZ_AEOU01000121.1::G00012Context members
EFME4452_RS10060EFME4452_RS10065
Partner locus tags
EFME4452_RS10060EFME4452_RS10065
Partner old locus tags
EfmE4452_2311EfmE4452_2312
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_002326482.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4452_RS10065Primary locus identifier stored in the genes table.
Old locus tagEfmE4452_2312Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEOU01000121.1Sequence record reported by the local genomic context database.
Genomic interval6 428-7 495 nt1 068 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 789-7 495 ntGCF_000239115::NZ_AEOU01000121.1::G00012
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239115::NZ_AEOU01000121.1::G00012Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEOU01000121.1All displayed genes belong to this local TCS context.
Neighborhood span5 789-7 495 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 789 nt7 495 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4452_RS10060GCF_000239115#EFME4452_RS10060
RRNarL
5 789-6 421 nt · Reverse (-)
EFME4452_RS10065GCF_000239115#EFME4452_RS10065
HKClassicCurrent focus
6 428-7 495 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000239115#EFME4452_RS10065The current gene is the representative for this cluster.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2775103
Simplified PFAM architecture for HKOC_2775103
PFAM domain coverage: 159 / 355 aa (44.8%)
1 aa355 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[155-223] | HATPase_c[262-351]
- Domain count: 2
- Matched identifier: HKOC_2775103
- Positioned domains: HisKA_3 155-223 ; HATPase_c 262-351
Cluster members and taxonomy
Representative gene: GCF_000239115#EFME4452_RS10065
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 933 356 · GCF_000239115
AssemblyASM23911v2 · Contighaploid
Genome composition2 769 032 bp · 38,0% GCEnterococcus faecium E4452
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key