1 Response_reg#1
4-119 aa · 116 aa · 22.2% of protein
Raw token
Response_reg:4:3.75e-28:119:117:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME4452_RS09580
Response regulator, unclassified
Enterococcus faecium E4452 · GCF_000239115
ClassRRTypeunclassifiedLength522 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000239115#EFME4452_RS09580Stable P2CS identifier used across views.
GenomeGCF_000239115Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
Response_regHTH_AraC
Protein length522 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage197 / 522 aa (37.7%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa522 aa
Domain-by-domain annotation3 items
2 HTH_AraC#2
420-462 aa · 43 aa · 8.2% of protein
Raw token
HTH_AraC:420:0.00000214:462:43:423 HTH_AraC#3
475-512 aa · 38 aa · 7.3% of protein
Raw token
HTH_AraC:475:0.0000000105:512:38:42- Raw architecture: Response_reg:4:3.75e-28:119:117:111#HTH_AraC:420:0.00000214:462:43:42#HTH_AraC:475:0.0000000105:512:38:42
- Domain description: 1 Response_reg,2 HTH_AraC
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000239115::NZ_AEOU01000109.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5173-8185Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE4452_1705RefSeq proteinWP_002323446.1
Context group ID
GCF_000239115::NZ_AEOU01000109.1::G00013Context members
EFME4452_RS09575EFME4452_RS09580
Partner locus tags
EFME4452_RS09575EFME4452_RS09580
Partner old locus tags
EfmE4452_1704EfmE4452_1705
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002323446.1Primary protein accession used for annex mappings.
UniProt accessionA0AB37VVB5Primary UniProt accession resolved in the annex database.
UniProt IDA0AB37VVB5_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME4452_RS09580Primary locus identifier stored in the genes table.
Old locus tagEfmE4452_1705Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEOU01000109.1Sequence record reported by the local genomic context database.
Genomic interval6 617-8 185 nt1 569 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 173-8 185 ntGCF_000239115::NZ_AEOU01000109.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000239115::NZ_AEOU01000109.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEOU01000109.1All displayed genes belong to this local TCS context.
Neighborhood span5 173-8 185 nt3 013 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 173 nt8 185 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EFME4452_RS09575GCF_000239115#EFME4452_RS09575
HKClassic
5 173-6 624 nt · Forward (+)
EFME4452_RS09580GCF_000239115#EFME4452_RS09580
RRunclassifiedCurrent focus
6 617-8 185 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000239115#EFME4452_RS09580The current gene is the representative for this cluster.
PFAM architectureResponse_reg + HTH_182 domains in the representative PFAM annotation.
PFAM architecture for RROC_0122969
Simplified PFAM architecture for RROC_0122969
PFAM domain coverage: 194 / 522 aa (37.2%)
1 aa522 aa
Response_regHTH_18
- Simplified architecture: Response_reg + HTH_18
- Raw architecture: Response_reg[4-119] | HTH_18[435-512]
- Domain count: 2
- Matched identifier: RROC_0122969
- Positioned domains: Response_reg 4-119 ; Response_reg 4-119 ; HTH_18 435-512 ; HTH_18 435-512
Cluster members and taxonomy
Representative gene: GCF_000239115#EFME4452_RS09580
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 933 356 · GCF_000239115
AssemblyASM23911v2 · Contighaploid
Genome composition2 769 032 bp · 38,0% GCEnterococcus faecium E4452
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key