Gene detail

HMPREF9945_RS13235

Histidine kinase, Classic

Clostridioides difficile 70-100-2010 · GCF_000235905

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000235905#HMPREF9945_RS13235Stable P2CS identifier used across views.
GenomeGCF_000235905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842502Run 6 · 189 sequences · id 100% · cov 80% · representative
External referencesWP_021390475.1 · MIST4 HMPREF9945_RS13235RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF9945_RS13235
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000368:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:3.76e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000368:514:66:64#HATPase_c:565:3.76e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000235905::NZ_JH379248.1::G00015
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span52812-56306Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9945_00967RefSeq proteinWP_021390475.1
Context group IDGCF_000235905::NZ_JH379248.1::G00015
Context members
HMPREF9945_RS13240HMPREF9945_RS13235HMPREF9945_RS13230
Partner locus tags
HMPREF9945_RS13240HMPREF9945_RS13235HMPREF9945_RS13230
Partner old locus tags
HMPREF9945_00966HMPREF9945_00967HMPREF9945_00968

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021390475.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9945_RS13235Primary locus identifier stored in the genes table.
Old locus tagHMPREF9945_00967Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379248.1Sequence record reported by the local genomic context database.
Genomic interval53 561-55 576 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span52 812-56 306 ntGCF_000235905::NZ_JH379248.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000235905::NZ_JH379248.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379248.1All displayed genes belong to this local TCS context.
Neighborhood span52 812-56 306 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
52 812 nt56 306 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

HMPREF9945_RS13240GCF_000235905#HMPREF9945_RS13240
RROmpR

52 812-53 489 nt · Forward (+)

Old locus HMPREF9945_00966RefSeq WP_003417201.1
HMPREF9945_RS13230GCF_000235905#HMPREF9945_RS13230
RROmpR

55 626-56 306 nt · Forward (+)

Old locus HMPREF9945_00968RefSeq WP_003432361.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842502Run 6 · HK · 189 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS13235The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842502

Simplified PFAM architecture for HKOC_0842502

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842502
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS13235

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 002 369 · GCF_000235905
AssemblyASM23590v1 · Scaffoldhaploid
Genome composition4 008 217 bp · 28,5% GCClostridioides difficile 70-100-2010
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key