1 HAMP#1
252-320 aa · 69 aa · 10.8% of protein
Raw token
HAMP:252:8.55e-16:320:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ISE_RS0109735
Histidine kinase, Classic
Bifidobacterium breve DPC 6330 · GCF_000226175
ClassHKTypeClassicLength641 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000226175#ISE_RS0109735Stable P2CS identifier used across views.
GenomeGCF_000226175Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length641 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage287 / 641 aa (44.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa641 aa
Domain-by-domain annotation3 items
2 HisKA#2
332-401 aa · 70 aa · 10.9% of protein
Raw token
HisKA:332:7.41e-18:401:70:643 HATPase_c#3
465-612 aa · 148 aa · 23.1% of protein
Raw token
HATPase_c:465:4.79e-21:612:148:109- Raw architecture: HAMP:252:8.55e-16:320:69:69#HisKA:332:7.41e-18:401:70:64#HATPase_c:465:4.79e-21:612:148:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000226175::NZ_AFXX01000043.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span75738-78471Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000226175::NZ_AFXX01000043.1::G00002Context members
ISE_RS0109735ISE_RS0109740
Partner locus tags
ISE_RS0109735ISE_RS0109740
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_019728160.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagISE_RS0109735Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AFXX01000043.1Sequence record reported by the local genomic context database.
Genomic interval75 738-77 663 nt1 926 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span75 738-78 471 ntGCF_000226175::NZ_AFXX01000043.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000226175::NZ_AFXX01000043.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFXX01000043.1All displayed genes belong to this local TCS context.
Neighborhood span75 738-78 471 nt2 734 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
75 738 nt78 471 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ISE_RS0109735GCF_000226175#ISE_RS0109735
HKClassicCurrent focus
75 738-77 663 nt · Reverse (-)
ISE_RS0109740GCF_000226175#ISE_RS0109740
RROmpR
77 740-78 471 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000568955#B12L_RS06745Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0892113
Simplified PFAM architecture for HKOC_0892113
PFAM domain coverage: 268 / 652 aa (41.1%)
1 aa652 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[280-331] | HisKA[344-412] | HATPase_c[476-622]
- Domain count: 3
- Matched identifier: HKOC_0892113
- Positioned domains: HAMP 280-331 ; HisKA 344-412 ; HATPase_c 476-622
Cluster members and taxonomy
Representative gene: GCF_000568955#B12L_RS06745
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 074 482 · GCF_000226175
AssemblyASM22617v2 · Contighaploid
Genome composition2 386 233 bp · 58,5% GCBifidobacterium breve DPC 6330
Signal transduction countsGenes 20 · HK 9 · RR 11CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium
Related genes
Preview from the same derived genome key