Gene detail

CDM120_RS10950

Histidine kinase, Classic

Clostridioides difficile M120 · GCF_000210435

ClassHKTypeClassicLength425 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210435#CDM120_RS10950Stable P2CS identifier used across views.
GenomeGCF_000210435Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2216037Run 6 · 289 sequences · id 100% · cov 80%
External referencesWP_003424453.1 · D5Q3K1 · MIST4 CDM120_RS10950RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length425 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 425 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for CDM120_RS10950
Domain-by-domain annotation2 items
1 HisKA#1
196-260 aa · 65 aa · 15.3% of protein
Raw tokenHisKA:196:0.0000000000155:260:65:64
2 HATPase_c#2
307-424 aa · 118 aa · 27.8% of protein
Raw tokenHATPase_c:307:8.15e-19:424:119:109
  • Raw architecture: HisKA:196:0.0000000000155:260:65:64#HATPase_c:307:8.15e-19:424:119:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000210435::NC_017174.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2302470-2304399Genomic interval covered by the local TCS group.
Context group IDGCF_000210435::NC_017174.1::G00032
Context members
CDM120_RS10950CDM120_RS10955
Partner locus tags
CDM120_RS10950CDM120_RS10955
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003424453.1Primary protein accession used for annex mappings.
UniProt accessionD5Q3K1Primary UniProt accession resolved in the annex database.
UniProt IDD5Q3K1_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagCDM120_RS10950Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017174.1Sequence record reported by the local genomic context database.
Genomic interval2 302 470-2 303 747 nt1 278 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 302 470-2 304 399 ntGCF_000210435::NC_017174.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000210435::NC_017174.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017174.1All displayed genes belong to this local TCS context.
Neighborhood span2 302 470-2 304 399 nt1 930 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 302 470 nt2 304 399 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

CDM120_RS10955GCF_000210435#CDM120_RS10955
RROmpR

2 303 731-2 304 399 nt · Reverse (-)

RefSeq WP_003424455.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2216037Run 6 · HK · 289 sequences
Representative sequenceGCF_000155065#QAE_RS0210295Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2216037

Simplified PFAM architecture for HKOC_2216037

PFAM domain coverage: 179 / 425 aa (42.1%)

1 aa425 aa
HisKA: 197-260 aaHisKAHATPase_c: 308-422 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[197-260] | HATPase_c[308-422]
  • Domain count: 2
  • Matched identifier: HKOC_2216037
  • Positioned domains: HisKA 197-260 ; HATPase_c 308-422
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155065#QAE_RS0210295

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 699 035 · GCF_000210435
AssemblyASM21043v1 · Complete Genomehaploid
Genome composition4 047 729 bp · 28,5% GCClostridioides difficile M120
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key