1 HAMP#1
170-237 aa · 68 aa · 14.7% of protein
Raw token
HAMP:170:0.00000000000625:237:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
CDM120_RS03305
Histidine kinase, Classic
Clostridioides difficile M120 · GCF_000210435
ClassHKTypeClassicLength464 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000210435#CDM120_RS03305Stable P2CS identifier used across views.
GenomeGCF_000210435Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length464 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage213 / 464 aa (45.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
249-308 aa · 60 aa · 12.9% of protein
Raw token
HisKA:249:0.000000000254:308:61:643 HATPase_c#3
355-439 aa · 85 aa · 18.3% of protein
Raw token
HATPase_c:355:0.00000000000000176:439:88:109- Raw architecture: HAMP:170:0.00000000000625:237:68:69#HisKA:249:0.000000000254:308:61:64#HATPase_c:355:0.00000000000000176:439:88:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000210435::NC_017174.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span622944-624978Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000210435::NC_017174.1::G00005Context members
CDM120_RS03300CDM120_RS03305
Partner locus tags
CDM120_RS03300CDM120_RS03305
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417837.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0A2Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0A2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagCDM120_RS03305Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNC_017174.1Sequence record reported by the local genomic context database.
Genomic interval623 584-624 978 nt1 395 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span622 944-624 978 ntGCF_000210435::NC_017174.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000210435::NC_017174.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017174.1All displayed genes belong to this local TCS context.
Neighborhood span622 944-624 978 nt2 035 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
622 944 nt624 978 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
CDM120_RS03300GCF_000210435#CDM120_RS03300
RROmpR
622 944-623 591 nt · Forward (+)
CDM120_RS03305GCF_000210435#CDM120_RS03305
HKClassicCurrent focus
623 584-624 978 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0202465Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1783726
Simplified PFAM architecture for HKOC_1783726
PFAM domain coverage: 195 / 464 aa (42.0%)
1 aa464 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[187-236] | HisKA[250-308] | HATPase_c[355-440]
- Domain count: 3
- Matched identifier: HKOC_1783726
- Positioned domains: HAMP 187-236 ; HisKA 250-308 ; HATPase_c 355-440
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0202465
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 699 035 · GCF_000210435
AssemblyASM21043v1 · Complete Genomehaploid
Genome composition4 047 729 bp · 28,5% GCClostridioides difficile M120
Signal transduction countsGenes 97 · HK 48 · RR 49CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key