1 PBPb#1
73-276 aa · 204 aa · 17.0% of protein
Raw token
PBPb:73:0.0000000000000231:276:209:219P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC970246_RS17975
Histidine kinase, Unorthodox
Escherichia coli 97.0246 · GCF_000194215
ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000194215#EC970246_RS17975Stable P2CS identifier used across views.
GenomeGCF_000194215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PBPbHisKAHATPase_cResponse_regHpt
Protein length1197 aaLength used to scale native and Biotite-like views.
Annotated domains66 with usable coordinates.
Domain coverage796 / 1197 aa (66.5%)Merged over positioned domains only.
Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1197 aa
Domain-by-domain annotation6 items
2 PBPb#2
304-519 aa · 216 aa · 18.0% of protein
Raw token
PBPb:304:2.67e-38:519:223:2193 HisKA#3
711-777 aa · 67 aa · 5.6% of protein
Raw token
HisKA:711:3.14e-16:777:67:644 HATPase_c#4
825-938 aa · 114 aa · 9.5% of protein
Raw token
HATPase_c:825:4.83e-31:938:114:1095 Response_reg#5
961-1070 aa · 110 aa · 9.2% of protein
Raw token
Response_reg:961:1.96e-39:1070:110:1116 Hpt#6
1104-1188 aa · 85 aa · 7.1% of protein
Raw token
Hpt:1104:0.000000465:1188:85:84- Raw architecture: PBPb:73:0.0000000000000231:276:209:219#PBPb:304:2.67e-38:519:223:219#HisKA:711:3.14e-16:777:67:64#HATPase_c:825:4.83e-31:938:114:109#Response_reg:961:1.96e-39:1070:110:111#Hpt:1104:0.000000465:1188:85:84
- Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000194215::NZ_AEZJ02000012.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span315774-319986Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEC970246_1264RefSeq proteinWP_024177748.1
Context group ID
GCF_000194215::NZ_AEZJ02000012.1::G00028Context members
EC970246_RS17980EC970246_RS17975
Partner locus tags
EC970246_RS17980EC970246_RS17975
Partner old locus tags
EC970246_1263EC970246_1264
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_024177748.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC970246_RS17975Primary locus identifier stored in the genes table.
Old locus tagEC970246_1264Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEZJ02000012.1Sequence record reported by the local genomic context database.
Genomic interval316 393-319 986 nt3 594 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span315 774-319 986 ntGCF_000194215::NZ_AEZJ02000012.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000194215::NZ_AEZJ02000012.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEZJ02000012.1All displayed genes belong to this local TCS context.
Neighborhood span315 774-319 986 nt4 213 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
315 774 nt319 986 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EC970246_RS17980GCF_000194215#EC970246_RS17980
RRunclassified
315 774-316 388 nt · Forward (+)
EC970246_RS17975GCF_000194215#EC970246_RS17975
HKUnorthodoxCurrent focus
316 393-319 986 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000194215#EC970246_RS17975The current gene is the representative for this cluster.
PFAM architectureSBP_bac_3 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0161064
Simplified PFAM architecture for HKOC_0161064
PFAM domain coverage: 505 / 1197 aa (42.2%)
1 aa1197 aa
SBP_bac_3HisKAHATPase_cResponse_reg
- Simplified architecture: SBP_bac_3 + HisKA + HATPase_c + Response_reg
- Raw architecture: SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070]
- Domain count: 4
- Matched identifier: HKOC_0161064
- Positioned domains: SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070
Cluster members and taxonomy
Representative gene: GCF_000194215#EC970246_RS17975
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 670 · GCF_000194215
AssemblyASM19421v2 · Contighaploid
Genome composition5 497 467 bp · 50,5% GCEscherichia coli 97.0246
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key