1 HAMP#1
188-257 aa · 70 aa · 14.5% of protein
Raw token
HAMP:188:0.0000000000532:257:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC970246_RS00100
Histidine kinase, Classic
Escherichia coli 97.0246 · GCF_000194215
ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000194215#EC970246_RS00100Stable P2CS identifier used across views.
GenomeGCF_000194215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 482 aa (51.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
Domain-by-domain annotation3 items
2 HisKA#2
261-327 aa · 67 aa · 13.9% of protein
Raw token
HisKA:261:0.00000000000129:327:67:643 HATPase_c#3
371-482 aa · 112 aa · 23.2% of protein
Raw token
HATPase_c:371:2.69e-29:482:113:109- Raw architecture: HAMP:188:0.0000000000532:257:71:69#HisKA:261:0.00000000000129:327:67:64#HATPase_c:371:2.69e-29:482:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000194215::NZ_AEZJ02000048.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span210008-212129Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEC970246_0678RefSeq proteinWP_000253830.1
Context group ID
GCF_000194215::NZ_AEZJ02000048.1::G00003Context members
EC970246_RS00105EC970246_RS00100
Partner locus tags
EC970246_RS00105EC970246_RS00100
Partner old locus tags
EC970246_0677EC970246_0678
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000253830.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KSG8Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KSG8_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC970246_RS00100Primary locus identifier stored in the genes table.
Old locus tagEC970246_0678Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEZJ02000048.1Sequence record reported by the local genomic context database.
Genomic interval210 681-212 129 nt1 449 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span210 008-212 129 ntGCF_000194215::NZ_AEZJ02000048.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000194215::NZ_AEZJ02000048.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEZJ02000048.1All displayed genes belong to this local TCS context.
Neighborhood span210 008-212 129 nt2 122 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
210 008 nt212 129 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EC970246_RS00105GCF_000194215#EC970246_RS00105
RROmpR
210 008-210 691 nt · Forward (+)
EC970246_RS00100GCF_000194215#EC970246_RS00100
HKClassicCurrent focus
210 681-212 129 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_009649155#GIY15_RS13115Use this link to inspect the representative gene detail.
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1543826
Simplified PFAM architecture for HKOC_1543826
PFAM domain coverage: 397 / 489 aa (81.2%)
1 aa489 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-180] | HAMP[210-257] | HisKA[262-326] | HATPase_c[371-481]
- Domain count: 4
- Matched identifier: HKOC_1543826
- Positioned domains: CusS 8-180 ; HAMP 210-257 ; HisKA 262-326 ; HATPase_c 371-481
Cluster members and taxonomy
Representative gene: GCF_009649155#GIY15_RS13115
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 670 · GCF_000194215
AssemblyASM19421v2 · Contighaploid
Genome composition5 497 467 bp · 50,5% GCEscherichia coli 97.0246
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key