1 HAMP#1
175-243 aa · 69 aa · 14.5% of protein
Raw token
HAMP:175:0.00000313:243:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC970246_RS17100
Histidine kinase, Classic
Escherichia coli 97.0246 · GCF_000194215
ClassHKTypeClassicLength475 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000194215#EC970246_RS17100Stable P2CS identifier used across views.
GenomeGCF_000194215Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length475 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 475 aa (51.6%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa475 aa
Domain-by-domain annotation3 items
2 HisKA#2
249-316 aa · 68 aa · 14.3% of protein
Raw token
HisKA:249:0.0000000000000168:316:68:643 HATPase_c#3
362-469 aa · 108 aa · 22.7% of protein
Raw token
HATPase_c:362:1.81e-23:469:108:109- Raw architecture: HAMP:175:0.00000313:243:69:69#HisKA:249:0.0000000000000168:316:68:64#HATPase_c:362:1.81e-23:469:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000194215::NZ_AEZJ02000012.1::G00032
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span510816-512243Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEC970246_1459RefSeq proteinWP_001364844.1
Context group ID
GCF_000194215::NZ_AEZJ02000012.1::G00032Context members
EC970246_RS17100
Partner locus tags
EC970246_RS17100
Partner old locus tags
EC970246_1459
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001364844.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FQH1Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FQH1_ECOLXDisplay identifier provided by UniProt.
GO / PubMed6 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC970246_RS17100Primary locus identifier stored in the genes table.
Old locus tagEC970246_1459Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AEZJ02000012.1Sequence record reported by the local genomic context database.
Genomic interval510 816-512 243 nt1 428 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span510 816-512 243 ntGCF_000194215::NZ_AEZJ02000012.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000194215::NZ_AEZJ02000012.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AEZJ02000012.1All displayed genes belong to this local TCS context.
Neighborhood span510 816-512 243 nt1 428 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
510 816 nt512 243 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EC970246_RS17100GCF_000194215#EC970246_RS17100
HKClassicCurrent focus
510 816-512 243 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000194215#EC970246_RS17100The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1664497
Simplified PFAM architecture for HKOC_1664497
PFAM domain coverage: 176 / 475 aa (37.1%)
1 aa475 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[250-316] | HATPase_c[362-470]
- Domain count: 2
- Matched identifier: HKOC_1664497
- Positioned domains: HisKA 250-316 ; HATPase_c 362-470
Cluster members and taxonomy
Representative gene: GCF_000194215#EC970246_RS17100
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 869 670 · GCF_000194215
AssemblyASM19421v2 · Contighaploid
Genome composition5 497 467 bp · 50,5% GCEscherichia coli 97.0246
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key