1 PAS_3#1
172-235 aa · 64 aa · 8.0% of protein
Raw token
PAS_3:172:0.000000726:235:64:89P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS23360
Histidine kinase, Hybrid
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeHybridLength801 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS23360Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
PAS_3HisKAHATPase_cResponse_reg
Protein length801 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage382 / 801 aa (47.7%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa801 aa
Domain-by-domain annotation4 items
2 HisKA#2
404-486 aa · 83 aa · 10.4% of protein
Raw token
HisKA:404:0.0000000000193:486:83:643 HATPase_c#3
534-650 aa · 117 aa · 14.6% of protein
Raw token
HATPase_c:534:4.11e-33:650:117:1094 Response_reg#4
679-796 aa · 118 aa · 14.7% of protein
Raw token
Response_reg:679:4.04e-30:796:118:111- Raw architecture: PAS_3:172:0.000000726:235:64:89#HisKA:404:0.0000000000193:486:83:64#HATPase_c:534:4.11e-33:650:117:109#Response_reg:679:4.04e-30:796:118:111
- Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000189595::NZ_GL834324.1::G00063
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span2698-5103Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_04523RefSeq proteinWP_003505109.1
Context group ID
GCF_000189595::NZ_GL834324.1::G00063Context members
HMPREF9474_RS23360
Partner locus tags
HMPREF9474_RS23360
Partner old locus tags
HMPREF9474_04523
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003505109.1Primary protein accession used for annex mappings.
UniProt accessionE7GUC8Primary UniProt accession resolved in the annex database.
UniProt IDE7GUC8_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS23360Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_04523Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834324.1Sequence record reported by the local genomic context database.
Genomic interval2 698-5 103 nt2 406 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 698-5 103 ntGCF_000189595::NZ_GL834324.1::G00063
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834324.1::G00063Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834324.1All displayed genes belong to this local TCS context.
Neighborhood span2 698-5 103 nt2 406 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 698 nt5 103 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF9474_RS23360GCF_000189595#HMPREF9474_RS23360
HKHybridCurrent focus
2 698-5 103 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS23360The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0554217
Simplified PFAM architecture for HKOC_0554217
PFAM domain coverage: 314 / 801 aa (39.2%)
1 aa801 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[404-486] | HATPase_c[534-649] | Response_reg[679-793]
- Domain count: 3
- Matched identifier: HKOC_0554217
- Positioned domains: HisKA 404-486 ; HATPase_c 534-649 ; Response_reg 679-793
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS23360
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key