1 HAMP#1
238-305 aa · 68 aa · 12.8% of protein
Raw token
HAMP:238:0.0000000000196:305:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS22880
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength531 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS22880Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length531 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 531 aa (49.2%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa531 aa
Domain-by-domain annotation3 items
2 His_kinase#2
322-401 aa · 80 aa · 15.1% of protein
Raw token
His_kinase:322:7.6e-33:401:80:803 HATPase_c#3
413-525 aa · 113 aa · 21.3% of protein
Raw token
HATPase_c:413:0.0000000000000257:525:114:109- Raw architecture: HAMP:238:0.0000000000196:305:68:69#His_kinase:322:7.6e-33:401:80:80#HATPase_c:413:0.0000000000000257:525:114:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834322.1::G00060
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span13003-15706Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_04435RefSeq proteinWP_003504918.1
Context group ID
GCF_000189595::NZ_GL834322.1::G00060Context members
HMPREF9474_RS22875HMPREF9474_RS22880
Partner locus tags
HMPREF9474_RS22875HMPREF9474_RS22880
Partner old locus tags
HMPREF9474_04434HMPREF9474_04435
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003504918.1Primary protein accession used for annex mappings.
UniProt accessionE7GU40Primary UniProt accession resolved in the annex database.
UniProt IDE7GU40_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS22880Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_04435Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834322.1Sequence record reported by the local genomic context database.
Genomic interval14 111-15 706 nt1 596 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span13 003-15 706 ntGCF_000189595::NZ_GL834322.1::G00060
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834322.1::G00060Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834322.1All displayed genes belong to this local TCS context.
Neighborhood span13 003-15 706 nt2 704 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
13 003 nt15 706 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS22875GCF_000189595#HMPREF9474_RS22875
RRunclassified
13 003-14 121 nt · Forward (+)
HMPREF9474_RS22880GCF_000189595#HMPREF9474_RS22880
HKClassicCurrent focus
14 111-15 706 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS22880The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1351635
Simplified PFAM architecture for HKOC_1351635
PFAM domain coverage: 241 / 531 aa (45.4%)
1 aa531 aa
HAMPHis_kinaseHATPase_c
- Simplified architecture: HAMP + His_kinase + HATPase_c
- Raw architecture: HAMP[256-305] | His_kinase[322-399] | HATPase_c[414-526]
- Domain count: 3
- Matched identifier: HKOC_1351635
- Positioned domains: HAMP 256-305 ; His_kinase 322-399 ; HATPase_c 414-526
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS22880
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key