Gene detail

HMPREF9474_RS21960

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS21960Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2800996Run 6 · 58 sequences · id 100% · cov 80% · representative
External referencesWP_003504606.1 · E7GTL8 · MIST4 HMPREF9474_RS21960RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

His_kinaseHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage187 / 349 aa (53.6%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
His_kinase: 122-201 aa (80 aa)1HATPase_c: 228-334 aa (107 aa)2
Domain-by-domain annotation2 items
1 His_kinase#1
122-201 aa · 80 aa · 22.9% of protein
Raw tokenHis_kinase:122:3.47e-32:201:80:80
2 HATPase_c#2
228-334 aa · 107 aa · 30.7% of protein
Raw tokenHATPase_c:228:0.0000000000000256:334:107:109
  • Raw architecture: His_kinase:122:3.47e-32:201:80:80#HATPase_c:228:0.0000000000000256:334:107:109
  • Domain description: 1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834320.1::G00059
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span58838-61515Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_04263RefSeq proteinWP_003504606.1
Context group IDGCF_000189595::NZ_GL834320.1::G00059
Context members
HMPREF9474_RS21960HMPREF9474_RS21965
Partner locus tags
HMPREF9474_RS21960HMPREF9474_RS21965
Partner old locus tags
HMPREF9474_04263HMPREF9474_04264
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003504606.1Primary protein accession used for annex mappings.
UniProt accessionE7GTL8Primary UniProt accession resolved in the annex database.
UniProt IDE7GTL8_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS21960Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_04263Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834320.1Sequence record reported by the local genomic context database.
Genomic interval58 838-59 887 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span58 838-61 515 ntGCF_000189595::NZ_GL834320.1::G00059

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834320.1::G00059

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834320.1All displayed genes belong to this local TCS context.
Neighborhood span58 838-61 515 nt2 678 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
58 838 nt61 515 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS21965GCF_000189595#HMPREF9474_RS21965
RRunclassified

59 926-61 515 nt · Reverse (-)

Old locus HMPREF9474_04264RefSeq WP_003504608.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2800996Run 6 · HK · 58 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS21960The current gene is the representative for this cluster.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2800996

Simplified PFAM architecture for HKOC_2800996

PFAM domain coverage: 191 / 349 aa (54.7%)

1 aa349 aa
His_kinase: 122-201 aaHis_kinaseHATPase_c: 225-335 aaHATPase_c
His_kinaseHATPase_c
  • Simplified architecture: His_kinase + HATPase_c
  • Raw architecture: His_kinase[122-201] | HATPase_c[225-335]
  • Domain count: 2
  • Matched identifier: HKOC_2800996
  • Positioned domains: His_kinase 122-201 ; HATPase_c 225-335
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS21960

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key