Gene detail

HMPREF9474_RS19995

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeHybridLength1032 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS19995Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0269729Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_003503816.1 · E7GSI6 · MIST4 HMPREF9474_RS19995RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GGDEFHisKAHATPase_cResponse_reg
Protein length1032 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage454 / 1032 aa (44.0%)Merged over positioned domains only.
Domain description1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1032 aa
GGDEF: 305-457 aa (153 aa)1HisKA: 651-717 aa (67 aa)2HATPase_c: 764-880 aa (117 aa)3Response_reg: 906-1022 aa (117 aa)4
Domain-by-domain annotation4 items
1 GGDEF#1
305-457 aa · 153 aa · 14.8% of protein
Raw tokenGGDEF:305:1.36e-20:457:160:160
2 HisKA#2
651-717 aa · 67 aa · 6.5% of protein
Raw tokenHisKA:651:2.34e-17:717:67:64
3 HATPase_c#3
764-880 aa · 117 aa · 11.3% of protein
Raw tokenHATPase_c:764:2.82e-32:880:117:109
4 Response_reg#4
906-1022 aa · 117 aa · 11.3% of protein
Raw tokenResponse_reg:906:1.14e-31:1022:117:111
  • Raw architecture: GGDEF:305:1.36e-20:457:160:160#HisKA:651:2.34e-17:717:67:64#HATPase_c:764:2.82e-32:880:117:109#Response_reg:906:1.14e-31:1022:117:111
  • Domain description: 1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189595::NZ_GL834317.1::G00053
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span82973-86071Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_03881RefSeq proteinWP_003503816.1
Context group IDGCF_000189595::NZ_GL834317.1::G00053
Context members
HMPREF9474_RS19995
Partner locus tags
HMPREF9474_RS19995
Partner old locus tags
HMPREF9474_03881
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003503816.1Primary protein accession used for annex mappings.
UniProt accessionE7GSI6Primary UniProt accession resolved in the annex database.
UniProt IDE7GSI6_CLOS6Display identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
GO terms

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS19995Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_03881Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834317.1Sequence record reported by the local genomic context database.
Genomic interval82 973-86 071 nt3 099 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span82 973-86 071 ntGCF_000189595::NZ_GL834317.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834317.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834317.1All displayed genes belong to this local TCS context.
Neighborhood span82 973-86 071 nt3 099 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
82 973 nt86 071 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0269729Run 6 · HK · 3 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS19995The current gene is the representative for this cluster.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0269729

Simplified PFAM architecture for HKOC_0269729

PFAM domain coverage: 449 / 1032 aa (43.5%)

1 aa1032 aa
GGDEF: 305-455 aaGGDEFHisKA: 651-717 aaHisKAHATPase_c: 765-879 aaHATPase_cResponse_reg: 906-1021 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[305-455] | HisKA[651-717] | HATPase_c[765-879] | Response_reg[906-1021]
  • Domain count: 4
  • Matched identifier: HKOC_0269729
  • Positioned domains: GGDEF 305-455 ; HisKA 651-717 ; HATPase_c 765-879 ; Response_reg 906-1021
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS19995

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key