1 HAMP#1
233-304 aa · 72 aa · 13.0% of protein
Raw token
HAMP:233:0.000000000000564:304:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS14475
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength554 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS14475Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length554 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage249 / 554 aa (44.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa554 aa
Domain-by-domain annotation3 items
2 HisKA#2
329-396 aa · 68 aa · 12.3% of protein
Raw token
HisKA:329:0.00000000000000265:396:68:643 HATPase_c#3
441-549 aa · 109 aa · 19.7% of protein
Raw token
HATPase_c:441:1.11e-21:549:110:109- Raw architecture: HAMP:233:0.000000000000564:304:72:69#HisKA:329:0.00000000000000265:396:68:64#HATPase_c:441:1.11e-21:549:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834312.1::G00045
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5182-7520Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02825RefSeq proteinWP_003501636.1
Context group ID
GCF_000189595::NZ_GL834312.1::G00045Context members
HMPREF9474_RS14470HMPREF9474_RS14475
Partner locus tags
HMPREF9474_RS14470HMPREF9474_RS14475
Partner old locus tags
HMPREF9474_02824HMPREF9474_02825
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003501636.1Primary protein accession used for annex mappings.
UniProt accessionE7GPJ7Primary UniProt accession resolved in the annex database.
UniProt IDE7GPJ7_CLOS6Display identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS14475Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02825Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834312.1Sequence record reported by the local genomic context database.
Genomic interval5 856-7 520 nt1 665 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span5 182-7 520 ntGCF_000189595::NZ_GL834312.1::G00045
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834312.1::G00045Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834312.1All displayed genes belong to this local TCS context.
Neighborhood span5 182-7 520 nt2 339 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 182 nt7 520 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS14470GCF_000189595#HMPREF9474_RS14470
RROmpR
5 182-5 859 nt · Forward (+)
HMPREF9474_RS14475GCF_000189595#HMPREF9474_RS14475
HKClassicCurrent focus
5 856-7 520 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS14475The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1280822
Simplified PFAM architecture for HKOC_1280822
PFAM domain coverage: 176 / 554 aa (31.8%)
1 aa554 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[329-394] | HATPase_c[441-550]
- Domain count: 2
- Matched identifier: HKOC_1280822
- Positioned domains: HisKA 329-394 ; HATPase_c 441-550
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS14475
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key