Gene detail

HMPREF9474_RS13170

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeHybridLength852 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS13170Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0484749Run 6 · 3 sequences · id 100% · cov 80% · representative
External referencesWP_195481630.1 · MIST4 HMPREF9474_RS13170RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HisKAHATPase_cResponse_reg
Protein length852 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage536 / 852 aa (62.9%)Merged over positioned domains only.
Domain description1 dCache_1,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa852 aa
dCache_1: 165-281 aa (117 aa)1HisKA: 344-410 aa (67 aa)2HATPase_c: 458-576 aa (119 aa)3Response_reg: 592-706 aa (115 aa)4Response_reg: 731-848 aa (118 aa)5
Domain-by-domain annotation5 items
1 dCache_1#1
165-281 aa · 117 aa · 13.7% of protein
Raw tokendCache_1:165:0.000057:281:118:195
2 HisKA#2
344-410 aa · 67 aa · 7.9% of protein
Raw tokenHisKA:344:4.87e-17:410:67:64
3 HATPase_c#3
458-576 aa · 119 aa · 14.0% of protein
Raw tokenHATPase_c:458:5.27e-27:576:119:109
4 Response_reg#4
592-706 aa · 115 aa · 13.5% of protein
Raw tokenResponse_reg:592:3.46e-22:706:115:111
5 Response_reg#5
731-848 aa · 118 aa · 13.8% of protein
Raw tokenResponse_reg:731:2.53e-26:848:118:111
  • Raw architecture: dCache_1:165:0.000057:281:118:195#HisKA:344:4.87e-17:410:67:64#HATPase_c:458:5.27e-27:576:119:109#Response_reg:592:3.46e-22:706:115:111#Response_reg:731:2.53e-26:848:118:111
  • Domain description: 1 dCache_1,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834311.1::G00042
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span10246-14843Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02577RefSeq proteinWP_195481630.1
Context group IDGCF_000189595::NZ_GL834311.1::G00042
Context members
HMPREF9474_RS13160HMPREF9474_RS13170
Partner locus tags
HMPREF9474_RS13160HMPREF9474_RS13170
Partner old locus tags
HMPREF9474_02575HMPREF9474_02577
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_195481630.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS13170Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02577Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834311.1Sequence record reported by the local genomic context database.
Genomic interval12 285-14 843 nt2 559 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span10 246-14 843 ntGCF_000189595::NZ_GL834311.1::G00042

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834311.1::G00042

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834311.1All displayed genes belong to this local TCS context.
Neighborhood span10 246-14 843 nt4 598 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
10 246 nt14 843 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS13160GCF_000189595#HMPREF9474_RS13160
RRRpfG

10 246-11 898 nt · Forward (+)

Old locus HMPREF9474_02575RefSeq WP_003501149.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0484749Run 6 · HK · 3 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS13170The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0484749

Simplified PFAM architecture for HKOC_0484749

PFAM domain coverage: 415 / 852 aa (48.7%)

1 aa852 aa
HisKA: 344-410 aaHisKAHATPase_c: 458-575 aaHATPase_cResponse_reg: 592-705 aaResponse_regResponse_reg: 731-846 aaResponse_reg
HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: HisKA[344-410] | HATPase_c[458-575] | Response_reg[592-705] | Response_reg[731-846]
  • Domain count: 4
  • Matched identifier: HKOC_0484749
  • Positioned domains: HisKA 344-410 ; HATPase_c 458-575 ; Response_reg 592-705 ; Response_reg 731-846
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS13170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key