1 His_kinase#1
376-454 aa · 79 aa · 13.4% of protein
Raw token
His_kinase:376:2.54e-34:454:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS12880
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS12880Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage183 / 589 aa (31.1%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
473-576 aa · 104 aa · 17.7% of protein
Raw token
HATPase_c:473:2.55e-16:576:105:109- Raw architecture: His_kinase:376:2.54e-34:454:80:80#HATPase_c:473:2.55e-16:576:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834310.1::G00041
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span286464-288930Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02522RefSeq proteinWP_227072462.1
Context group ID
GCF_000189595::NZ_GL834310.1::G00041Context members
HMPREF9474_RS12875HMPREF9474_RS12880
Partner locus tags
HMPREF9474_RS12875HMPREF9474_RS12880
Partner old locus tags
HMPREF9474_02521HMPREF9474_02522
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_227072462.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS12880Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02522Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834310.1Sequence record reported by the local genomic context database.
Genomic interval287 161-288 930 nt1 770 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span286 464-288 930 ntGCF_000189595::NZ_GL834310.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834310.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834310.1All displayed genes belong to this local TCS context.
Neighborhood span286 464-288 930 nt2 467 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
286 464 nt288 930 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS12875GCF_000189595#HMPREF9474_RS12875
RRLytTR
286 464-287 183 nt · Reverse (-)
HMPREF9474_RS12880GCF_000189595#HMPREF9474_RS12880
HKClassicCurrent focus
287 161-288 930 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS12880The current gene is the representative for this cluster.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1114821
Simplified PFAM architecture for HKOC_1114821
PFAM domain coverage: 343 / 589 aa (58.2%)
1 aa589 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[48-205] | His_kinase[376-454] | HATPase_c[472-577]
- Domain count: 3
- Matched identifier: HKOC_1114821
- Positioned domains: 5TM-5TMR_LYT 48-205 ; His_kinase 376-454 ; HATPase_c 472-577
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS12880
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key