Gene detail

HMPREF9474_RS12635

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength351 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS12635Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2792607Run 6 · 8 sequences · id 100% · cov 80% · representative
External referencesWP_202883084.1 · MIST4 HMPREF9474_RS12635RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length351 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage307 / 351 aa (87.5%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa351 aa
H_kinase_N: 7-143 aa (137 aa)1HisKA_2: 163-237 aa (75 aa)2HATPase_c: 257-351 aa (95 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
7-143 aa · 137 aa · 39.0% of protein
Raw tokenH_kinase_N:7:1.38e-34:143:137:139
2 HisKA_2#2
163-237 aa · 75 aa · 21.4% of protein
Raw tokenHisKA_2:163:5.62e-23:237:76:76
3 HATPase_c#3
257-351 aa · 95 aa · 27.1% of protein
Raw tokenHATPase_c:257:0.00000000000299:351:111:109
  • Raw architecture: H_kinase_N:7:1.38e-34:143:137:139#HisKA_2:163:5.62e-23:237:76:76#HATPase_c:257:0.00000000000299:351:111:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834310.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span234240-236019Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02473RefSeq proteinWP_202883084.1
Context group IDGCF_000189595::NZ_GL834310.1::G00039
Context members
HMPREF9474_RS12635HMPREF9474_RS12640
Partner locus tags
HMPREF9474_RS12635HMPREF9474_RS12640
Partner old locus tags
HMPREF9474_02473HMPREF9474_02474
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_202883084.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS12635Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02473Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834310.1Sequence record reported by the local genomic context database.
Genomic interval234 240-235 295 nt1 056 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span234 240-236 019 ntGCF_000189595::NZ_GL834310.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834310.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834310.1All displayed genes belong to this local TCS context.
Neighborhood span234 240-236 019 nt1 780 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
234 240 nt236 019 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS12640GCF_000189595#HMPREF9474_RS12640
RRAmiR_NasR

235 297-236 019 nt · Reverse (-)

Old locus HMPREF9474_02474RefSeq WP_003500926.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2792607Run 6 · HK · 8 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS12635The current gene is the representative for this cluster.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2792607

Simplified PFAM architecture for HKOC_2792607

PFAM domain coverage: 305 / 351 aa (86.9%)

1 aa351 aa
GAF_PdtaS: 6-143 aaGAF_PdtaSHisKA_2: 163-237 aaHisKA_2HATPase_c: 259-350 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[6-143] | HisKA_2[163-237] | HATPase_c[259-350]
  • Domain count: 3
  • Matched identifier: HKOC_2792607
  • Positioned domains: GAF_PdtaS 6-143 ; HisKA_2 163-237 ; HATPase_c 259-350
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS12635

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key