1 sCache_2#1
176-288 aa · 113 aa · 15.5% of protein
Raw token
sCache_2:176:0.000000000178:288:115:152P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS11270
Histidine kinase, Hybrid
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeHybridLength728 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS11270Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
sCache_2HisKAHATPase_cResponse_reg
Protein length728 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage410 / 728 aa (56.3%)Merged over positioned domains only.
Domain description1 sCache_2,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa728 aa
Domain-by-domain annotation4 items
2 HisKA#2
356-417 aa · 62 aa · 8.5% of protein
Raw token
HisKA:356:0.000000124:417:62:643 HATPase_c#3
463-587 aa · 125 aa · 17.2% of protein
Raw token
HATPase_c:463:4.55e-26:587:126:1094 Response_reg#4
613-722 aa · 110 aa · 15.1% of protein
Raw token
Response_reg:613:0.0000000000000348:722:114:111- Raw architecture: sCache_2:176:0.000000000178:288:115:152#HisKA:356:0.000000124:417:62:64#HATPase_c:463:4.55e-26:587:126:109#Response_reg:613:0.0000000000000348:722:114:111
- Domain description: 1 sCache_2,1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000189595::NZ_GL834309.1::G00036
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span301168-303354Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02198RefSeq proteinWP_003500352.1
Context group ID
GCF_000189595::NZ_GL834309.1::G00036Context members
HMPREF9474_RS11270
Partner locus tags
HMPREF9474_RS11270
Partner old locus tags
HMPREF9474_02198
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003500352.1Primary protein accession used for annex mappings.
UniProt accessionE7GMQ3Primary UniProt accession resolved in the annex database.
UniProt IDE7GMQ3_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS11270Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02198Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834309.1Sequence record reported by the local genomic context database.
Genomic interval301 168-303 354 nt2 187 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span301 168-303 354 ntGCF_000189595::NZ_GL834309.1::G00036
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834309.1::G00036Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834309.1All displayed genes belong to this local TCS context.
Neighborhood span301 168-303 354 nt2 187 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
301 168 nt303 354 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF9474_RS11270GCF_000189595#HMPREF9474_RS11270
HKHybridCurrent focus
301 168-303 354 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_028207415#PMZ71_RS23020Use this link to inspect the representative gene detail.
PFAM architecturesCache_2 + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0642609
Simplified PFAM architecture for HKOC_0642609
PFAM domain coverage: 416 / 761 aa (54.7%)
1 aa761 aa
sCache_2HisKAHATPase_cResponse_reg
- Simplified architecture: sCache_2 + HisKA + HATPase_c + Response_reg
- Raw architecture: sCache_2[202-318] | HisKA[390-452] | HATPase_c[496-621] | Response_reg[646-755]
- Domain count: 4
- Matched identifier: HKOC_0642609
- Positioned domains: sCache_2 202-318 ; HisKA 390-452 ; HATPase_c 496-621 ; Response_reg 646-755
Cluster members and taxonomy
Representative gene: GCF_028207415#PMZ71_RS23020
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key