1 PAS_3#1
47-118 aa · 72 aa · 8.8% of protein
Raw token
PAS_3:47:0.00000822:118:72:89P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS11110
Histidine kinase, Hybrid
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeHybridLength814 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS11110Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
PAS_3HisKAHATPase_cResponse_reg
Protein length814 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage481 / 814 aa (59.1%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa814 aa
Domain-by-domain annotation5 items
2 HisKA#2
297-363 aa · 67 aa · 8.2% of protein
Raw token
HisKA:297:6.68e-16:363:67:643 HATPase_c#3
410-527 aa · 118 aa · 14.5% of protein
Raw token
HATPase_c:410:2.09e-28:527:118:1094 Response_reg#4
547-653 aa · 107 aa · 13.1% of protein
Raw token
Response_reg:547:1.64e-18:653:107:1115 Response_reg#5
691-807 aa · 117 aa · 14.4% of protein
Raw token
Response_reg:691:5.59e-31:807:117:111- Raw architecture: PAS_3:47:0.00000822:118:72:89#HisKA:297:6.68e-16:363:67:64#HATPase_c:410:2.09e-28:527:118:109#Response_reg:547:1.64e-18:653:107:111#Response_reg:691:5.59e-31:807:117:111
- Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000189595::NZ_GL834309.1::G00034
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span260905-263349Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02165RefSeq proteinWP_003500288.1
Context group ID
GCF_000189595::NZ_GL834309.1::G00034Context members
HMPREF9474_RS11110
Partner locus tags
HMPREF9474_RS11110
Partner old locus tags
HMPREF9474_02165
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003500288.1Primary protein accession used for annex mappings.
UniProt accessionE7GMM0Primary UniProt accession resolved in the annex database.
UniProt IDE7GMM0_CLOS6Display identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS11110Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02165Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834309.1Sequence record reported by the local genomic context database.
Genomic interval260 905-263 349 nt2 445 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span260 905-263 349 ntGCF_000189595::NZ_GL834309.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834309.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834309.1All displayed genes belong to this local TCS context.
Neighborhood span260 905-263 349 nt2 445 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
260 905 nt263 349 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF9474_RS11110GCF_000189595#HMPREF9474_RS11110
HKHybridCurrent focus
260 905-263 349 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS11110The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg + Response_reg4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0535481
Simplified PFAM architecture for HKOC_0535481
PFAM domain coverage: 414 / 814 aa (50.9%)
1 aa814 aa
HisKAHATPase_cResponse_regResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg + Response_reg
- Raw architecture: HisKA[297-363] | HATPase_c[410-526] | Response_reg[547-660] | Response_reg[691-806]
- Domain count: 4
- Matched identifier: HKOC_0535481
- Positioned domains: HisKA 297-363 ; HATPase_c 410-526 ; Response_reg 547-660 ; Response_reg 691-806
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS11110
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key