Gene detail

HMPREF9474_RS11085

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength416 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS11085Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2302340Run 6 · 14 sequences · id 100% · cov 80% · representative
External referencesWP_242827608.1 · A0AAW6AXA4 · MIST4 HMPREF9474_RS11085RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length416 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 416 aa (58.9%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa416 aa
HAMP: 100-166 aa (67 aa)1HisKA: 191-256 aa (66 aa)2HATPase_c: 302-413 aa (112 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
100-166 aa · 67 aa · 16.1% of protein
Raw tokenHAMP:100:0.0000000000104:166:67:69
2 HisKA#2
191-256 aa · 66 aa · 15.9% of protein
Raw tokenHisKA:191:0.000000122:256:66:64
3 HATPase_c#3
302-413 aa · 112 aa · 26.9% of protein
Raw tokenHATPase_c:302:4.97e-24:413:113:109
  • Raw architecture: HAMP:100:0.0000000000104:166:67:69#HisKA:191:0.000000122:256:66:64#HATPase_c:302:4.97e-24:413:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834309.1::G00033
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span254721-256653Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02160RefSeq proteinWP_242827608.1
Context group IDGCF_000189595::NZ_GL834309.1::G00033
Context members
HMPREF9474_RS11080HMPREF9474_RS11085
Partner locus tags
HMPREF9474_RS11080HMPREF9474_RS11085
Partner old locus tags
HMPREF9474_02159HMPREF9474_02160
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_242827608.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6AXA4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6AXA4_CLOSYDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS11085Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02160Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834309.1Sequence record reported by the local genomic context database.
Genomic interval255 403-256 653 nt1 251 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span254 721-256 653 ntGCF_000189595::NZ_GL834309.1::G00033

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834309.1::G00033

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834309.1All displayed genes belong to this local TCS context.
Neighborhood span254 721-256 653 nt1 933 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
254 721 nt256 653 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS11080GCF_000189595#HMPREF9474_RS11080
RROmpR

254 721-255 413 nt · Forward (+)

Old locus HMPREF9474_02159RefSeq WP_003500275.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2302340Run 6 · HK · 14 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS11085The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2302340

Simplified PFAM architecture for HKOC_2302340

PFAM domain coverage: 226 / 416 aa (54.3%)

1 aa416 aa
HAMP: 114-165 aaHAMPHisKA: 193-256 aaHisKAHATPase_c: 303-412 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[114-165] | HisKA[193-256] | HATPase_c[303-412]
  • Domain count: 3
  • Matched identifier: HKOC_2302340
  • Positioned domains: HAMP 114-165 ; HisKA 193-256 ; HATPase_c 303-412
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS11085

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key