1 HisKA#1
193-255 aa · 63 aa · 15.4% of protein
Raw token
HisKA:193:0.00000000000146:255:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS11030
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength408 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS11030Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length408 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 408 aa (41.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa408 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
300-406 aa · 107 aa · 26.2% of protein
Raw token
HATPase_c:300:5.09e-23:406:111:109- Raw architecture: HisKA:193:0.00000000000146:255:64:64#HATPase_c:300:5.09e-23:406:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834309.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span244171-246068Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02149RefSeq proteinWP_003500255.1
Context group ID
GCF_000189595::NZ_GL834309.1::G00032Context members
HMPREF9474_RS11025HMPREF9474_RS11030
Partner locus tags
HMPREF9474_RS11025HMPREF9474_RS11030
Partner old locus tags
HMPREF9474_02148HMPREF9474_02149
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003500255.1Primary protein accession used for annex mappings.
UniProt accessionE7GMK4Primary UniProt accession resolved in the annex database.
UniProt IDE7GMK4_CLOS6Display identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS11030Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02149Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834309.1Sequence record reported by the local genomic context database.
Genomic interval244 842-246 068 nt1 227 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span244 171-246 068 ntGCF_000189595::NZ_GL834309.1::G00032
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834309.1::G00032Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834309.1All displayed genes belong to this local TCS context.
Neighborhood span244 171-246 068 nt1 898 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
244 171 nt246 068 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS11025GCF_000189595#HMPREF9474_RS11025
RROmpR
244 171-244 848 nt · Forward (+)
HMPREF9474_RS11030GCF_000189595#HMPREF9474_RS11030
HKClassicCurrent focus
244 842-246 068 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS11030The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2371309
Simplified PFAM architecture for HKOC_2371309
PFAM domain coverage: 168 / 408 aa (41.2%)
1 aa408 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[194-255] | HATPase_c[301-406]
- Domain count: 2
- Matched identifier: HKOC_2371309
- Positioned domains: HisKA 194-255 ; HATPase_c 301-406
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS11030
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key