Gene detail

HMPREF9474_RS10740

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength383 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS10740Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_2582151Run 6 · 56 sequences · id 100% · cov 80% · representative
External referencesWP_003500147.1 · E7GME6 · MIST4 HMPREF9474_RS10740RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length383 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage245 / 383 aa (64.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa383 aa
HAMP: 87-156 aa (70 aa)1HisKA: 160-226 aa (67 aa)2HATPase_c: 272-379 aa (108 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
87-156 aa · 70 aa · 18.3% of protein
Raw tokenHAMP:87:0.000000000116:156:70:69
2 HisKA#2
160-226 aa · 67 aa · 17.5% of protein
Raw tokenHisKA:160:0.0000000000011:226:67:64
3 HATPase_c#3
272-379 aa · 108 aa · 28.2% of protein
Raw tokenHATPase_c:272:3.96e-30:379:108:109
  • Raw architecture: HAMP:87:0.000000000116:156:70:69#HisKA:160:0.0000000000011:226:67:64#HATPase_c:272:3.96e-30:379:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000189595::NZ_GL834309.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span181265-183090Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_02091RefSeq proteinWP_003500147.1
Context group IDGCF_000189595::NZ_GL834309.1::G00030
Context members
HMPREF9474_RS10735HMPREF9474_RS10740
Partner locus tags
HMPREF9474_RS10735HMPREF9474_RS10740
Partner old locus tags
HMPREF9474_02090HMPREF9474_02091
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003500147.1Primary protein accession used for annex mappings.
UniProt accessionE7GME6Primary UniProt accession resolved in the annex database.
UniProt IDE7GME6_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS10740Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_02091Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834309.1Sequence record reported by the local genomic context database.
Genomic interval181 939-183 090 nt1 152 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span181 265-183 090 ntGCF_000189595::NZ_GL834309.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834309.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834309.1All displayed genes belong to this local TCS context.
Neighborhood span181 265-183 090 nt1 826 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
181 265 nt183 090 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9474_RS10735GCF_000189595#HMPREF9474_RS10735
RROmpR

181 265-181 942 nt · Forward (+)

Old locus HMPREF9474_02090RefSeq WP_003500146.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2582151Run 6 · HK · 56 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS10740The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2582151

Simplified PFAM architecture for HKOC_2582151

PFAM domain coverage: 227 / 383 aa (59.3%)

1 aa383 aa
HAMP: 103-155 aaHAMPHisKA: 160-225 aaHisKAHATPase_c: 271-378 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[103-155] | HisKA[160-225] | HATPase_c[271-378]
  • Domain count: 3
  • Matched identifier: HKOC_2582151
  • Positioned domains: HAMP 103-155 ; HisKA 160-225 ; HATPase_c 271-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS10740

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key