Gene detail

HMPREF9474_RS07820

Histidine kinase, Hybrid

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeHybridLength1318 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS07820Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_0116505Run 6 · 6 sequences · id 100% · cov 80% · representative
External referencesWP_024738262.1 · A0AAW5F4A5 · MIST4 HMPREF9474_RS07820RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3GGDEFHisKAHATPase_cResponse_reg
Protein length1318 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage513 / 1318 aa (38.9%)Merged over positioned domains only.
Domain description1 PAS_3,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa1318 aa
PAS_3: 512-570 aa (59 aa)1GGDEF: 587-733 aa (147 aa)2HisKA: 939-1005 aa (67 aa)3HATPase_c: 1051-1172 aa (122 aa)4Response_reg: 1198-1315 aa (118 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
512-570 aa · 59 aa · 4.5% of protein
Raw tokenPAS_3:512:0.0000309:570:63:89
2 GGDEF#2
587-733 aa · 147 aa · 11.2% of protein
Raw tokenGGDEF:587:0.0000000000104:733:159:160
3 HisKA#3
939-1005 aa · 67 aa · 5.1% of protein
Raw tokenHisKA:939:7.7e-17:1005:67:64
4 HATPase_c#4
1051-1172 aa · 122 aa · 9.3% of protein
Raw tokenHATPase_c:1051:1.47e-28:1172:122:109
5 Response_reg#5
1198-1315 aa · 118 aa · 9.0% of protein
Raw tokenResponse_reg:1198:2.32e-31:1315:118:111
  • Raw architecture: PAS_3:512:0.0000309:570:63:89#GGDEF:587:0.0000000000104:733:159:160#HisKA:939:7.7e-17:1005:67:64#HATPase_c:1051:1.47e-28:1172:122:109#Response_reg:1198:2.32e-31:1315:118:111
  • Domain description: 1 PAS_3,1 GGDEF,1 HisKA,1 HATPase_c,1 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189595::NZ_GL834307.1::G00026
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span241322-245278Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_01517RefSeq proteinWP_024738262.1
Context group IDGCF_000189595::NZ_GL834307.1::G00026
Context members
HMPREF9474_RS07820
Partner locus tags
HMPREF9474_RS07820
Partner old locus tags
HMPREF9474_01517
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_024738262.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW5F4A5Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW5F4A5_CLOSYDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS07820Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_01517Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834307.1Sequence record reported by the local genomic context database.
Genomic interval241 322-245 278 nt3 957 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span241 322-245 278 ntGCF_000189595::NZ_GL834307.1::G00026

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834307.1::G00026

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834307.1All displayed genes belong to this local TCS context.
Neighborhood span241 322-245 278 nt3 957 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
241 322 nt245 278 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0116505Run 6 · HK · 6 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS07820The current gene is the representative for this cluster.
PFAM architectureGGDEF + HisKA + HATPase_c + Response_reg4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0116505

Simplified PFAM architecture for HKOC_0116505

PFAM domain coverage: 459 / 1318 aa (34.8%)

1 aa1318 aa
GGDEF: 588-741 aaGGDEFHisKA: 940-1005 aaHATPase_c: 1052-1172 aaHATPase_cResponse_reg: 1198-1315 aaResponse_reg
GGDEFHisKAHATPase_cResponse_reg
  • Simplified architecture: GGDEF + HisKA + HATPase_c + Response_reg
  • Raw architecture: GGDEF[588-741] | HisKA[940-1005] | HATPase_c[1052-1172] | Response_reg[1198-1315]
  • Domain count: 4
  • Matched identifier: HKOC_0116505
  • Positioned domains: GGDEF 588-741 ; HisKA 940-1005 ; HATPase_c 1052-1172 ; Response_reg 1198-1315
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS07820

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key