1 HAMP#1
56-124 aa · 69 aa · 19.3% of protein
Raw token
HAMP:56:0.00000000000459:124:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS05125
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength358 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS05125Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length358 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage244 / 358 aa (68.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa358 aa
Domain-by-domain annotation3 items
2 HisKA#2
131-194 aa · 64 aa · 17.9% of protein
Raw token
HisKA:131:0.00000000000000174:194:64:643 HATPase_c#3
240-350 aa · 111 aa · 31.0% of protein
Raw token
HATPase_c:240:1.53e-32:350:111:109- Raw architecture: HAMP:56:0.00000000000459:124:69:69#HisKA:131:0.00000000000000174:194:64:64#HATPase_c:240:1.53e-32:350:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834306.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span314186-315936Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00993RefSeq proteinWP_003498995.1
Context group ID
GCF_000189595::NZ_GL834306.1::G00021Context members
HMPREF9474_RS05120HMPREF9474_RS05125
Partner locus tags
HMPREF9474_RS05120HMPREF9474_RS05125
Partner old locus tags
HMPREF9474_00992HMPREF9474_00993
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003498995.1Primary protein accession used for annex mappings.
UniProt accessionE7GJA0Primary UniProt accession resolved in the annex database.
UniProt IDE7GJA0_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS05125Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00993Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834306.1Sequence record reported by the local genomic context database.
Genomic interval314 860-315 936 nt1 077 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span314 186-315 936 ntGCF_000189595::NZ_GL834306.1::G00021
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834306.1::G00021Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834306.1All displayed genes belong to this local TCS context.
Neighborhood span314 186-315 936 nt1 751 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
314 186 nt315 936 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS05120GCF_000189595#HMPREF9474_RS05120
RROmpR
314 186-314 863 nt · Forward (+)
HMPREF9474_RS05125GCF_000189595#HMPREF9474_RS05125
HKClassicCurrent focus
314 860-315 936 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS05125The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2758967
Simplified PFAM architecture for HKOC_2758967
PFAM domain coverage: 222 / 358 aa (62.0%)
1 aa358 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[78-124] | HisKA[131-195] | HATPase_c[240-349]
- Domain count: 3
- Matched identifier: HKOC_2758967
- Positioned domains: HAMP 78-124 ; HisKA 131-195 ; HATPase_c 240-349
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS05125
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key