1 HAMP#1
271-347 aa · 77 aa · 13.6% of protein
Raw token
HAMP:271:0.0000000189:347:77:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS03420
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength565 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS03420Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHis_kinaseHATPase_c
Protein length565 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage258 / 565 aa (45.7%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa565 aa
Domain-by-domain annotation3 items
2 His_kinase#2
363-440 aa · 78 aa · 13.8% of protein
Raw token
His_kinase:363:3.61e-28:440:79:803 HATPase_c#3
457-559 aa · 103 aa · 18.2% of protein
Raw token
HATPase_c:457:0.0000000355:559:106:109- Raw architecture: HAMP:271:0.0000000189:347:77:69#His_kinase:363:3.61e-28:440:79:80#HATPase_c:457:0.0000000355:559:106:109
- Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834305.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span809196-811685Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00659RefSeq proteinWP_003498274.1
Context group ID
GCF_000189595::NZ_GL834305.1::G00014Context members
HMPREF9474_RS03415HMPREF9474_RS03420
Partner locus tags
HMPREF9474_RS03415HMPREF9474_RS03420
Partner old locus tags
HMPREF9474_00658HMPREF9474_00659
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003498274.1Primary protein accession used for annex mappings.
UniProt accessionE7GIB6Primary UniProt accession resolved in the annex database.
UniProt IDE7GIB6_CLOS6Display identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS03420Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00659Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834305.1Sequence record reported by the local genomic context database.
Genomic interval809 988-811 685 nt1 698 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span809 196-811 685 ntGCF_000189595::NZ_GL834305.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834305.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834305.1All displayed genes belong to this local TCS context.
Neighborhood span809 196-811 685 nt2 490 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
809 196 nt811 685 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS03415GCF_000189595#HMPREF9474_RS03415
RRunclassified
809 196-809 984 nt · Reverse (-)
HMPREF9474_RS03420GCF_000189595#HMPREF9474_RS03420
HKClassicCurrent focus
809 988-811 685 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS03420The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1234116
Simplified PFAM architecture for HKOC_1234116
PFAM domain coverage: 124 / 565 aa (21.9%)
1 aa565 aa
HAMPHis_kinase
- Simplified architecture: HAMP + His_kinase
- Raw architecture: HAMP[302-347] | His_kinase[363-440]
- Domain count: 2
- Matched identifier: HKOC_1234116
- Positioned domains: HAMP 302-347 ; His_kinase 363-440
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS03420
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key