1 HAMP#1
145-216 aa · 72 aa · 16.1% of protein
Raw token
HAMP:145:0.000000000954:216:72:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9474_RS02070
Histidine kinase, Classic
[Clostridium] symbiosum WAL-14163 · GCF_000189595
ClassHKTypeClassicLength448 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000189595#HMPREF9474_RS02070Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length448 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 448 aa (52.5%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa448 aa
Domain-by-domain annotation3 items
2 HisKA#2
226-284 aa · 59 aa · 13.2% of protein
Raw token
HisKA:226:0.00000000251:284:59:643 HATPase_c#3
331-434 aa · 104 aa · 23.2% of protein
Raw token
HATPase_c:331:6.79e-21:434:107:109- Raw architecture: HAMP:145:0.000000000954:216:72:69#HisKA:226:0.00000000251:284:59:64#HATPase_c:331:6.79e-21:434:107:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000189595::NZ_GL834305.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span491322-494016Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00394RefSeq proteinWP_003497758.1
Context group ID
GCF_000189595::NZ_GL834305.1::G00007Context members
HMPREF9474_RS02065HMPREF9474_RS02070
Partner locus tags
HMPREF9474_RS02065HMPREF9474_RS02070
Partner old locus tags
HMPREF9474_00393HMPREF9474_00394
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003497758.1Primary protein accession used for annex mappings.
UniProt accessionE7GHK1Primary UniProt accession resolved in the annex database.
UniProt IDE7GHK1_CLOS6Display identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9474_RS02070Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00394Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834305.1Sequence record reported by the local genomic context database.
Genomic interval492 670-494 016 nt1 347 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span491 322-494 016 ntGCF_000189595::NZ_GL834305.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000189595::NZ_GL834305.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834305.1All displayed genes belong to this local TCS context.
Neighborhood span491 322-494 016 nt2 695 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
491 322 nt494 016 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9474_RS02065GCF_000189595#HMPREF9474_RS02065
RRunclassified
491 322-492 695 nt · Reverse (-)
HMPREF9474_RS02070GCF_000189595#HMPREF9474_RS02070
HKClassicCurrent focus
492 670-494 016 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000189595#HMPREF9474_RS02070The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1987865
Simplified PFAM architecture for HKOC_1987865
PFAM domain coverage: 216 / 448 aa (48.2%)
1 aa448 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[162-215] | HisKA[226-284] | HATPase_c[332-434]
- Domain count: 3
- Matched identifier: HKOC_1987865
- Positioned domains: HAMP 162-215 ; HisKA 226-284 ; HATPase_c 332-434
Cluster members and taxonomy
Representative gene: GCF_000189595#HMPREF9474_RS02070
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium
Related genes
Preview from the same derived genome key