Gene detail

HMPREF9474_RS00875

Histidine kinase, Classic

[Clostridium] symbiosum WAL-14163 · GCF_000189595

ClassHKTypeClassicLength608 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000189595#HMPREF9474_RS00875Stable P2CS identifier used across views.
GenomeGCF_000189595Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium
Selected clusterHKOC_1013064Run 6 · 43 sequences · id 100% · cov 80% · representative
External referencesWP_009297477.1 · A0AAW6B249 · MIST4 HMPREF9474_RS00875RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

dCache_1HisKAHATPase_c
Protein length608 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage309 / 608 aa (50.8%)Merged over positioned domains only.
Domain description1 dCache_1,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa608 aa
dCache_1: 134-280 aa (147 aa)1HisKA: 386-443 aa (58 aa)2HATPase_c: 499-602 aa (104 aa)3
Domain-by-domain annotation3 items
1 dCache_1#1
134-280 aa · 147 aa · 24.2% of protein
Raw tokendCache_1:134:1.93e-18:280:151:195
2 HisKA#2
386-443 aa · 58 aa · 9.5% of protein
Raw tokenHisKA:386:0.000000000114:443:58:64
3 HATPase_c#3
499-602 aa · 104 aa · 17.1% of protein
Raw tokenHATPase_c:499:3.53e-26:602:104:109
  • Raw architecture: dCache_1:134:1.93e-18:280:151:195#HisKA:386:0.000000000114:443:58:64#HATPase_c:499:3.53e-26:602:104:109
  • Domain description: 1 dCache_1,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000189595::NZ_GL834305.1::G00005
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span209302-211128Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9474_00160RefSeq proteinWP_009297477.1
Context group IDGCF_000189595::NZ_GL834305.1::G00005
Context members
HMPREF9474_RS00875
Partner locus tags
HMPREF9474_RS00875
Partner old locus tags
HMPREF9474_00160
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009297477.1Primary protein accession used for annex mappings.
UniProt accessionA0AAW6B249Primary UniProt accession resolved in the annex database.
UniProt IDA0AAW6B249_CLOSYDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9474_RS00875Primary locus identifier stored in the genes table.
Old locus tagHMPREF9474_00160Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_GL834305.1Sequence record reported by the local genomic context database.
Genomic interval209 302-211 128 nt1 827 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span209 302-211 128 ntGCF_000189595::NZ_GL834305.1::G00005

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000189595::NZ_GL834305.1::G00005

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_GL834305.1All displayed genes belong to this local TCS context.
Neighborhood span209 302-211 128 nt1 827 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
209 302 nt211 128 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1013064Run 6 · HK · 43 sequences
Representative sequenceGCF_000189595#HMPREF9474_RS00875The current gene is the representative for this cluster.
PFAM architecturedCache_1 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1013064

Simplified PFAM architecture for HKOC_1013064

PFAM domain coverage: 390 / 608 aa (64.1%)

1 aa608 aa
dCache_1: 54-281 aadCache_1HisKA: 386-443 aaHisKAHATPase_c: 500-603 aaHATPase_c
dCache_1HisKAHATPase_c
  • Simplified architecture: dCache_1 + HisKA + HATPase_c
  • Raw architecture: dCache_1[54-281] | HisKA[386-443] | HATPase_c[500-603]
  • Domain count: 3
  • Matched identifier: HKOC_1013064
  • Positioned domains: dCache_1 54-281 ; HisKA 386-443 ; HATPase_c 500-603
Cluster members and taxonomy
Visualization

Representative gene: GCF_000189595#HMPREF9474_RS00875

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 742 740 · GCF_000189595
AssemblyClos_symb_WAL_14163_V1 · Scaffoldhaploid
Genome composition5 352 498 bp · 47,5% GC[Clostridium] symbiosum WAL-14163
Signal transduction countsGenes 111 · HK 54 · RR 54CheA 0 · PP 3
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusLachnoclostridium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Lachnoclostridium

Related genes

Preview from the same derived genome key