1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw token
HAMP:72:0.000000837:139:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9347_RS19385
Histidine kinase, Classic
Escherichia coli MS 124-1 · GCF_000179135
ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000179135#HMPREF9347_RS19385Stable P2CS identifier used across views.
GenomeGCF_000179135Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
Domain-by-domain annotation3 items
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw token
HisKA:147:0.00000000177:204:61:643 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw token
HATPase_c:252:7.49e-22:360:111:109- Raw architecture: HAMP:72:0.000000837:139:68:69#HisKA:147:0.00000000177:204:61:64#HATPase_c:252:7.49e-22:360:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000179135::NZ_ADWT01000007.1::G00029
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span139106-140875Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9347_01386RefSeq proteinWP_001051093.1
Context group ID
GCF_000179135::NZ_ADWT01000007.1::G00029Context members
HMPREF9347_RS19385HMPREF9347_RS19380
Partner locus tags
HMPREF9347_RS19385HMPREF9347_RS19380
Partner old locus tags
HMPREF9347_01386HMPREF9347_01387
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001051093.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FI81Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FI81_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9347_RS19385Primary locus identifier stored in the genes table.
Old locus tagHMPREF9347_01386Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ADWT01000007.1Sequence record reported by the local genomic context database.
Genomic interval139 106-140 206 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span139 106-140 875 ntGCF_000179135::NZ_ADWT01000007.1::G00029
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000179135::NZ_ADWT01000007.1::G00029Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADWT01000007.1All displayed genes belong to this local TCS context.
Neighborhood span139 106-140 875 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
139 106 nt140 875 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9347_RS19385GCF_000179135#HMPREF9347_RS19385
HKClassicCurrent focus
139 106-140 206 nt · Reverse (-)
HMPREF9347_RS19380GCF_000179135#HMPREF9347_RS19380
RROmpR
140 207-140 875 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000010385#ECSE_RS22935Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2711915
Simplified PFAM architecture for HKOC_2711915
PFAM domain coverage: 165 / 366 aa (45.1%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-203] | HATPase_c[252-359]
- Domain count: 2
- Matched identifier: HKOC_2711915
- Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Representative gene: GCF_000010385#ECSE_RS22935
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 679 205 · GCF_000179135
AssemblyASM17913v1 · Contighaploid
Genome composition5 394 127 bp · 50,5% GCEscherichia coli MS 124-1
Signal transduction countsGenes 63 · HK 29 · RR 34CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key