1 Response_reg#1
6-108 aa · 103 aa · 29.5% of protein
Raw token
Response_reg:6:7.87e-27:108:105:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9347_RS01100
Response regulator, CheB family
Escherichia coli MS 124-1 · GCF_000179135
ClassRRTypeCheBLength349 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000179135#HMPREF9347_RS01100Stable P2CS identifier used across views.
GenomeGCF_000179135Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regCheB_methylest
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage282 / 349 aa (80.8%)Merged over positioned domains only.
Domain description1 Response_reg,1 CheB_methylestSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
Domain-by-domain annotation2 items
2 CheB_methylest#2
159-337 aa · 179 aa · 51.3% of protein
Raw token
CheB_methylest:159:3.44e-91:337:180:177- Raw architecture: Response_reg:6:7.87e-27:108:105:111#CheB_methylest:159:3.44e-91:337:180:177
- Domain description: 1 Response_reg,1 CheB_methylest
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000179135::NZ_ADWT01000116.1::G00001
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span161-1210Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9347_05815RefSeq proteinWP_000036371.1
Context group ID
GCF_000179135::NZ_ADWT01000116.1::G00001Context members
HMPREF9347_RS01100
Partner locus tags
HMPREF9347_RS01100
Partner old locus tags
HMPREF9347_05815
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000036371.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN4AXD3Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN4AXD3_SHIDYDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9347_RS01100Primary locus identifier stored in the genes table.
Old locus tagHMPREF9347_05815Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ADWT01000116.1Sequence record reported by the local genomic context database.
Genomic interval161-1 210 nt1 050 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span161-1 210 ntGCF_000179135::NZ_ADWT01000116.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000179135::NZ_ADWT01000116.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADWT01000116.1All displayed genes belong to this local TCS context.
Neighborhood span161-1 210 nt1 050 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
161 nt1 210 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF9347_RS01100GCF_000179135#HMPREF9347_RS01100
RRCheBCurrent focus
161-1 210 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007445#C_RS10880Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + CheB_methylest2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0481949
Simplified PFAM architecture for RROC_0481949
PFAM domain coverage: 281 / 349 aa (80.5%)
1 aa349 aa
Response_regCheB_methylest
- Simplified architecture: Response_reg + CheB_methylest
- Raw architecture: Response_reg[6-108] | CheB_methylest[159-336]
- Domain count: 2
- Matched identifier: RROC_0481949
- Positioned domains: Response_reg 6-108 ; Response_reg 6-108 ; CheB_methylest 159-336 ; CheB_methylest 159-336
Cluster members and taxonomy
Representative gene: GCF_000007445#C_RS10880
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 679 205 · GCF_000179135
AssemblyASM17913v1 · Contighaploid
Genome composition5 394 127 bp · 50,5% GCEscherichia coli MS 124-1
Signal transduction countsGenes 63 · HK 29 · RR 34CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key