1 HAMP#1
340-413 aa · 74 aa · 11.1% of protein
Raw token
HAMP:340:0.0000741:413:74:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9347_RS11490
Histidine kinase, Classic
Escherichia coli MS 124-1 · GCF_000179135
ClassHKTypeClassicLength669 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000179135#HMPREF9347_RS11490Stable P2CS identifier used across views.
GenomeGCF_000179135Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length669 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 669 aa (36.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa669 aa
Domain-by-domain annotation3 items
2 HisKA#2
450-512 aa · 63 aa · 9.4% of protein
Raw token
HisKA:450:0.00000909:512:63:643 HATPase_c#3
558-663 aa · 106 aa · 15.8% of protein
Raw token
HATPase_c:558:9.1e-19:663:109:109- Raw architecture: HAMP:340:0.0000741:413:74:69#HisKA:450:0.00000909:512:63:64#HATPase_c:558:9.1e-19:663:109:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000179135::NZ_ADWT01000028.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4511-7757Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9347_03267RefSeq proteinWP_000790444.1
Context group ID
GCF_000179135::NZ_ADWT01000028.1::G00017Context members
HMPREF9347_RS11490HMPREF9347_RS11485
Partner locus tags
HMPREF9347_RS11490HMPREF9347_RS11485
Partner old locus tags
HMPREF9347_03267HMPREF9347_03268
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000790444.1Primary protein accession used for annex mappings.
UniProt accessionA0A454A7Q5Primary UniProt accession resolved in the annex database.
UniProt IDA0A454A7Q5_ECOL5Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9347_RS11490Primary locus identifier stored in the genes table.
Old locus tagHMPREF9347_03267Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ADWT01000028.1Sequence record reported by the local genomic context database.
Genomic interval4 511-6 520 nt2 010 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 511-7 757 ntGCF_000179135::NZ_ADWT01000028.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000179135::NZ_ADWT01000028.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADWT01000028.1All displayed genes belong to this local TCS context.
Neighborhood span4 511-7 757 nt3 247 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 511 nt7 757 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9347_RS11490GCF_000179135#HMPREF9347_RS11490
HKClassicCurrent focus
4 511-6 520 nt · Forward (+)
HMPREF9347_RS11485GCF_000179135#HMPREF9347_RS11485
RRPrrA
6 510-7 757 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_035621835#VB129_RS21135Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0847133
Simplified PFAM architecture for HKOC_0847133
PFAM domain coverage: 169 / 670 aa (25.2%)
1 aa670 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[451-513] | HATPase_c[558-663]
- Domain count: 2
- Matched identifier: HKOC_0847133
- Positioned domains: HisKA 451-513 ; HATPase_c 558-663
Cluster members and taxonomy
Representative gene: GCF_035621835#VB129_RS21135
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 679 205 · GCF_000179135
AssemblyASM17913v1 · Contighaploid
Genome composition5 394 127 bp · 50,5% GCEscherichia coli MS 124-1
Signal transduction countsGenes 63 · HK 29 · RR 34CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key