1 Response_reg#1
8-118 aa · 111 aa · 26.7% of protein
Raw token
Response_reg:8:7.25e-38:118:111:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF9347_RS11485
Response regulator PrrA family
Escherichia coli MS 124-1 · GCF_000179135
ClassRRTypePrrALength415 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000179135#HMPREF9347_RS11485Stable P2CS identifier used across views.
GenomeGCF_000179135Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
Response_regHTH_8
Protein length415 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 415 aa (36.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa415 aa
Domain-by-domain annotation2 items
2 HTH_8#2
367-406 aa · 40 aa · 9.6% of protein
Raw token
HTH_8:367:0.0000000000676:406:40:40- Raw architecture: Response_reg:8:7.25e-38:118:111:111#HTH_8:367:0.0000000000676:406:40:40
- Domain description: 1 Response_reg,1 HTH_8
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000179135::NZ_ADWT01000028.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4511-7757Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9347_03268RefSeq proteinWP_000952905.1
Context group ID
GCF_000179135::NZ_ADWT01000028.1::G00017Context members
HMPREF9347_RS11490HMPREF9347_RS11485
Partner locus tags
HMPREF9347_RS11490HMPREF9347_RS11485
Partner old locus tags
HMPREF9347_03267HMPREF9347_03268
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000952905.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H0EAX9Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H0EAX9_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF9347_RS11485Primary locus identifier stored in the genes table.
Old locus tagHMPREF9347_03268Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ADWT01000028.1Sequence record reported by the local genomic context database.
Genomic interval6 510-7 757 nt1 248 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 511-7 757 ntGCF_000179135::NZ_ADWT01000028.1::G00017
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000179135::NZ_ADWT01000028.1::G00017Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ADWT01000028.1All displayed genes belong to this local TCS context.
Neighborhood span4 511-7 757 nt3 247 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 511 nt7 757 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF9347_RS11490GCF_000179135#HMPREF9347_RS11490
HKClassic
4 511-6 520 nt · Forward (+)
HMPREF9347_RS11485GCF_000179135#HMPREF9347_RS11485
RRPrrACurrent focus
6 510-7 757 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164215#HMPREF9536_RS07340Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activ_2 + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.
PFAM architecture for RROC_0361667
Simplified PFAM architecture for RROC_0361667
PFAM domain coverage: 341 / 415 aa (82.2%)
1 aa415 aa
Response_regSigma54_activ_2AAA_lid_14HTH_8
- Simplified architecture: Response_reg + Sigma54_activ_2 + AAA_lid_14 + HTH_8
- Raw architecture: Response_reg[8-117] | Sigma54_activ_2[143-278] | AAA_lid_14[285-338] | HTH_8[366-406]
- Domain count: 4
- Matched identifier: RROC_0361667
- Positioned domains: Response_reg 8-117 ; Response_reg 8-117 ; Sigma54_activ_2 143-278 ; Sigma54_activ_2 143-278 ; AAA_lid_14 285-338 ; AAA_lid_14 285-338 ; HTH_8 366-406 ; HTH_8 366-406
Cluster members and taxonomy
Representative gene: GCF_000164215#HMPREF9536_RS07340
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 679 205 · GCF_000179135
AssemblyASM17913v1 · Contighaploid
Genome composition5 394 127 bp · 50,5% GCEscherichia coli MS 124-1
Signal transduction countsGenes 63 · HK 29 · RR 34CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key