Gene detail

EFME1636_RS04405

Histidine kinase, Classic

Enterococcus faecium E1636 · GCF_000172835

ClassHKTypeClassicLength347 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000172835#EFME1636_RS04405Stable P2CS identifier used across views.
GenomeGCF_000172835Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2810211Run 6 · 1067 sequences · id 100% · cov 80%
External referencesWP_002294614.1 · A0A829F0D5 · MIST4 EFME1636_RS04405RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length347 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 347 aa (70.0%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa347 aa
HAMP: 54-123 aa (70 aa)1HisKA: 129-194 aa (66 aa)2HATPase_c: 238-344 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
54-123 aa · 70 aa · 20.2% of protein
Raw tokenHAMP:54:0.0000000136:123:70:69
2 HisKA#2
129-194 aa · 66 aa · 19.0% of protein
Raw tokenHisKA:129:0.00000000000000446:194:66:64
3 HATPase_c#3
238-344 aa · 107 aa · 30.8% of protein
Raw tokenHATPase_c:238:1.74e-31:344:107:109
  • Raw architecture: HAMP:54:0.0000000136:123:70:69#HisKA:129:0.00000000000000446:194:66:64#HATPase_c:238:1.74e-31:344:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000172835::NZ_ABRY01000011.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4573-6287Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE1636_0083RefSeq proteinWP_002294614.1
Context group IDGCF_000172835::NZ_ABRY01000011.1::G00020
Context members
EFME1636_RS04405EFME1636_RS04410
Partner locus tags
EFME1636_RS04405EFME1636_RS04410
Partner old locus tags
EfmE1636_0083EfmE1636_0084
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002294614.1Primary protein accession used for annex mappings.
UniProt accessionA0A829F0D5Primary UniProt accession resolved in the annex database.
UniProt IDA0A829F0D5_ENTFCDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEFME1636_RS04405Primary locus identifier stored in the genes table.
Old locus tagEfmE1636_0083Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABRY01000011.1Sequence record reported by the local genomic context database.
Genomic interval4 573-5 616 nt1 044 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 573-6 287 ntGCF_000172835::NZ_ABRY01000011.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000172835::NZ_ABRY01000011.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABRY01000011.1All displayed genes belong to this local TCS context.
Neighborhood span4 573-6 287 nt1 715 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 573 nt6 287 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EFME1636_RS04410GCF_000172835#EFME1636_RS04410
RROmpR

5 619-6 287 nt · Reverse (-)

Old locus EfmE1636_0084RefSeq WP_002297412.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2810211Run 6 · HK · 1067 sequences
Representative sequenceGCF_000172655#EFME1071_RS09220Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2810211

Simplified PFAM architecture for HKOC_2810211

PFAM domain coverage: 226 / 347 aa (65.1%)

1 aa347 aa
HAMP: 71-123 aaHAMPHisKA: 129-193 aaHisKAHATPase_c: 238-345 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[71-123] | HisKA[129-193] | HATPase_c[238-345]
  • Domain count: 3
  • Matched identifier: HKOC_2810211
  • Positioned domains: HAMP 71-123 ; HisKA 129-193 ; HATPase_c 238-345
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172655#EFME1071_RS09220

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 544 875 · GCF_000172835
AssemblyASM17283v1 · Contighaploid
Genome composition2 838 335 bp · 38,0% GCEnterococcus faecium E1636
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key