1 His_kinase#1
375-454 aa · 80 aa · 13.8% of protein
Raw token
His_kinase:375:3.92e-27:454:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EFME1162_RS12790
Histidine kinase, Classic
Enterococcus faecium E1162 · GCF_000172675
ClassHKTypeClassicLength578 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000172675#EFME1162_RS12790Stable P2CS identifier used across views.
GenomeGCF_000172675Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length578 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 578 aa (30.3%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa578 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
474-568 aa · 95 aa · 16.4% of protein
Raw token
HATPase_c:474:0.000000000134:568:105:109- Raw architecture: His_kinase:375:3.92e-27:454:80:80#HATPase_c:474:0.000000000134:568:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000172675::NZ_ABQJ01000037.1::G00013
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span29573-31309Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEfmE1162_0642RefSeq proteinWP_002289136.1
Context group ID
GCF_000172675::NZ_ABQJ01000037.1::G00013Context members
EFME1162_RS12790
Partner locus tags
EFME1162_RS12790
Partner old locus tags
EfmE1162_0642
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002289136.1Primary protein accession used for annex mappings.
UniProt accessionQ3XXZ8Primary UniProt accession resolved in the annex database.
UniProt IDQ3XXZ8_ENTFDDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEFME1162_RS12790Primary locus identifier stored in the genes table.
Old locus tagEfmE1162_0642Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABQJ01000037.1Sequence record reported by the local genomic context database.
Genomic interval29 573-31 309 nt1 737 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span29 573-31 309 ntGCF_000172675::NZ_ABQJ01000037.1::G00013
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000172675::NZ_ABQJ01000037.1::G00013Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABQJ01000037.1All displayed genes belong to this local TCS context.
Neighborhood span29 573-31 309 nt1 737 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 573 nt31 309 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EFME1162_RS12790GCF_000172675#EFME1162_RS12790
HKClassicCurrent focus
29 573-31 309 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147235#HMPREF9525_RS02205Use this link to inspect the representative gene detail.
PFAM architectureHis_kinase + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1172269
Simplified PFAM architecture for HKOC_1172269
PFAM domain coverage: 175 / 578 aa (30.3%)
1 aa578 aa
His_kinaseHATPase_c
- Simplified architecture: His_kinase + HATPase_c
- Raw architecture: His_kinase[376-454] | HATPase_c[473-568]
- Domain count: 2
- Matched identifier: HKOC_1172269
- Positioned domains: His_kinase 376-454 ; HATPase_c 473-568
Cluster members and taxonomy
Representative gene: GCF_000147235#HMPREF9525_RS02205
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 535 206 · GCF_000172675
AssemblyASM17267v1 · Contighaploid
Genome composition2 711 396 bp · 38,0% GCEnterococcus faecium E1162
Signal transduction countsGenes 33 · HK 16 · RR 17CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key