Gene detail

ECH7EC4401_RS14990

Histidine kinase, Classic

Escherichia coli O157:H7 str. EC4401 · GCF_000171975

ClassHKTypeClassicLength566 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000171975#ECH7EC4401_RS14990Stable P2CS identifier used across views.
GenomeGCF_000171975Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1228918Run 6 · 1394 sequences · id 100% · cov 80%
External referencesWP_001301838.1 · A0AAV3H7N4 · MIST4 ECH7EC4401_RS14990RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PilJHAMPHisKA_3HATPase_c
Protein length566 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage320 / 566 aa (56.5%)Merged over positioned domains only.
Domain description1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa566 aa
PilJ: 31-125 aa (95 aa)1HAMP: 154-224 aa (71 aa)2HisKA_3: 361-424 aa (64 aa)3HATPase_c: 467-556 aa (90 aa)4
Domain-by-domain annotation4 items
1 PilJ#1
31-125 aa · 95 aa · 16.8% of protein
Raw tokenPilJ:31:4.52e-17:125:111:112
2 HAMP#2
154-224 aa · 71 aa · 12.5% of protein
Raw tokenHAMP:154:0.0000000000023:224:71:69
3 HisKA_3#3
361-424 aa · 64 aa · 11.3% of protein
Raw tokenHisKA_3:361:1.98e-17:424:64:68
4 HATPase_c#4
467-556 aa · 90 aa · 15.9% of protein
Raw tokenHATPase_c:467:2.29e-19:556:105:109
  • Raw architecture: PilJ:31:4.52e-17:125:111:112#HAMP:154:0.0000000000023:224:71:69#HisKA_3:361:1.98e-17:424:64:68#HATPase_c:467:2.29e-19:556:105:109
  • Domain description: 1 PilJ,1 HAMP,1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000171975::NZ_ABHR01000014.1::G00020
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span43293-44993Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH7EC4401_1758RefSeq proteinWP_001301838.1
Context group IDGCF_000171975::NZ_ABHR01000014.1::G00020
Context members
ECH7EC4401_RS14990
Partner locus tags
ECH7EC4401_RS14990
Partner old locus tags
ECH7EC4401_1758
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001301838.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3H7N4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3H7N4_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECH7EC4401_RS14990Primary locus identifier stored in the genes table.
Old locus tagECH7EC4401_1758Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABHR01000014.1Sequence record reported by the local genomic context database.
Genomic interval43 293-44 993 nt1 701 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span43 293-44 993 ntGCF_000171975::NZ_ABHR01000014.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000171975::NZ_ABHR01000014.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABHR01000014.1All displayed genes belong to this local TCS context.
Neighborhood span43 293-44 993 nt1 701 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
43 293 nt44 993 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1228918Run 6 · HK · 1394 sequences
Representative sequenceGCF_000008865#ECs_3331Use this link to inspect the representative gene detail.
PFAM architecturePilJ + HAMP + HisKA_3 + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1228918

Simplified PFAM architecture for HKOC_1228918

PFAM domain coverage: 302 / 566 aa (53.4%)

1 aa566 aa
PilJ: 32-127 aaPilJHAMP: 172-223 aaHAMPHisKA_3: 361-424 aaHisKA_3HATPase_c: 467-556 aaHATPase_c
PilJHAMPHisKA_3HATPase_c
  • Simplified architecture: PilJ + HAMP + HisKA_3 + HATPase_c
  • Raw architecture: PilJ[32-127] | HAMP[172-223] | HisKA_3[361-424] | HATPase_c[467-556]
  • Domain count: 4
  • Matched identifier: HKOC_1228918
  • Positioned domains: PilJ 32-127 ; HAMP 172-223 ; HisKA_3 361-424 ; HATPase_c 467-556
Cluster members and taxonomy
Visualization

Representative gene: GCF_000008865#ECs_3331

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 478 004 · GCF_000171975
AssemblyASM17197v1 · Contighaploid
Genome composition5 733 133 bp · 50,5% GCEscherichia coli O157:H7 str. EC4401
Signal transduction countsGenes 60 · HK 28 · RR 32CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key