1 HAMP#1
164-232 aa · 69 aa · 15.4% of protein
Raw token
HAMP:164:0.00000165:232:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECH7EC4401_RS04380
Histidine kinase, Classic
Escherichia coli O157:H7 str. EC4401 · GCF_000171975
ClassHKTypeClassicLength449 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000171975#ECH7EC4401_RS04380Stable P2CS identifier used across views.
GenomeGCF_000171975Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length449 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 449 aa (50.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa449 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-301 aa · 64 aa · 14.3% of protein
Raw token
HisKA:238:0.00000000000418:301:64:643 HATPase_c#3
348-442 aa · 95 aa · 21.2% of protein
Raw token
HATPase_c:348:1.18e-25:442:99:109- Raw architecture: HAMP:164:0.00000165:232:70:69#HisKA:238:0.00000000000418:301:64:64#HATPase_c:348:1.18e-25:442:99:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000171975::NZ_ABHR01000002.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span213359-215364Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECH7EC4401_2936RefSeq proteinWP_000673362.1
Context group ID
GCF_000171975::NZ_ABHR01000002.1::G00035Context members
ECH7EC4401_RS04375ECH7EC4401_RS04380
Partner locus tags
ECH7EC4401_RS04375ECH7EC4401_RS04380
Partner old locus tags
ECH7EC4401_2935ECH7EC4401_2936
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000673362.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3H407Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3H407_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECH7EC4401_RS04380Primary locus identifier stored in the genes table.
Old locus tagECH7EC4401_2936Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_ABHR01000002.1Sequence record reported by the local genomic context database.
Genomic interval214 015-215 364 nt1 350 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span213 359-215 364 ntGCF_000171975::NZ_ABHR01000002.1::G00035
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000171975::NZ_ABHR01000002.1::G00035Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ABHR01000002.1All displayed genes belong to this local TCS context.
Neighborhood span213 359-215 364 nt2 006 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
213 359 nt215 364 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECH7EC4401_RS04375GCF_000171975#ECH7EC4401_RS04375
RROmpR
213 359-214 018 nt · Forward (+)
ECH7EC4401_RS04380GCF_000171975#ECH7EC4401_RS04380
HKClassicCurrent focus
214 015-215 364 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000006665#Z_RS20570Use this link to inspect the representative gene detail.
PFAM architecture2CSK_N + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1973160
Simplified PFAM architecture for HKOC_1973160
PFAM domain coverage: 297 / 449 aa (66.1%)
1 aa449 aa
2CSK_NHisKAHATPase_c
- Simplified architecture: 2CSK_N + HisKA + HATPase_c
- Raw architecture: 2CSK_N[23-157] | HisKA[237-301] | HATPase_c[349-445]
- Domain count: 3
- Matched identifier: HKOC_1973160
- Positioned domains: 2CSK_N 23-157 ; HisKA 237-301 ; HATPase_c 349-445
Cluster members and taxonomy
Representative gene: GCF_000006665#Z_RS20570
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 478 004 · GCF_000171975
AssemblyASM17197v1 · Contighaploid
Genome composition5 733 133 bp · 50,5% GCEscherichia coli O157:H7 str. EC4401
Signal transduction countsGenes 60 · HK 28 · RR 32CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key