Gene detail

EC53638_RS17965

Histidine kinase, Unorthodox

Escherichia coli 53638 · GCF_000167915

Open genome Open selected cluster RefSeq UniProt

ClassHKTypeUnorthodoxLength1197 aaTM0ValidatedNoCompleteYesContextpaired

Gene IDGCF_000167915#EC53638_RS17965Stable P2CS identifier used across views.

GenomeGCF_000167915Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia

Selected clusterHKOC_0161042Run 6 · 229 sequences · id 100% · cov 80% · representative

External referencesWP_001300674.1 · A0A369G034 · MIST4 EC53638_RS17965RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PBPbHisKAHATPase_cResponse_regHpt

Protein length1197 aaLength used to scale native and Biotite-like views.

Annotated domains66 with usable coordinates.

Domain coverage797 / 1197 aa (66.6%)Merged over positioned domains only.

Domain description2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.

Signal peptideUnavailableNo TMPRED prediction file matched this gene.

Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.

Complete domain annotations

Domain view

Native Biotite-like

Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.

1 aa1197 aa

Domain-by-domain annotation6 items

1 PBPb#1

73-276 aa · 204 aa · 17.0% of protein

Raw tokenPBPb:73:0.00000000000000543:276:209:219

2 PBPb#2

303-519 aa · 217 aa · 18.1% of protein

Raw tokenPBPb:303:8.28e-40:519:224:219

3 HisKA#3

711-777 aa · 67 aa · 5.6% of protein

Raw tokenHisKA:711:2.26e-16:777:67:64

4 HATPase_c#4

825-938 aa · 114 aa · 9.5% of protein

Raw tokenHATPase_c:825:1.52e-32:938:114:109

5 Response_reg#5

961-1070 aa · 110 aa · 9.2% of protein

Raw tokenResponse_reg:961:1.63e-39:1070:110:111

6 Hpt#6

1104-1188 aa · 85 aa · 7.1% of protein

Raw tokenHpt:1104:0.000000101:1188:85:84

Raw architecture: PBPb:73:0.00000000000000543:276:209:219#PBPb:303:8.28e-40:519:224:219#HisKA:711:2.26e-16:777:67:64#HATPase_c:825:1.52e-32:938:114:109#Response_reg:961:1.63e-39:1070:110:111#Hpt:1104:0.000000101:1188:85:84
Domain description: 2 PBPb,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
TM description: N/A
TMPRED source: No TMPRED file loaded
TMPRED segments: N/A
Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000167915::NZ_AAKB02000001.1::G00024

Group size22 locus tags listed below.

HK / RR1 / 1Counts resolved for the local TCS neighborhood.

Context span3570686-3574898Genomic interval covered by the local TCS group.

Identifiers

Old locus tagEc53638_3633RefSeq proteinWP_001300674.1

Context group IDGCF_000167915::NZ_AAKB02000001.1::G00024

Context members

EC53638_RS17965EC53638_RS17970

Partner locus tags

EC53638_RS17965EC53638_RS17970

Partner old locus tags

Ec53638_3633Ec53638_3634

Partner protein IDs

WP_001300674.1 WP_000991370.1

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001300674.1Primary protein accession used for annex mappings.

UniProt accessionA0A369G034Primary UniProt accession resolved in the annex database.

UniProt IDA0A369G034_ECOLXDisplay identifier provided by UniProt.

GO / PubMed4 / 0Unique GO terms and literature references available below.

Reference hubs

Open RefSeq Open UniProt accession

GO terms

GO:0005886 GO:0005524 GO:0009927 GO:0000155

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEC53638_RS17965Primary locus identifier stored in the genes table.

Old locus tagEc53638_3633Legacy locus tag recovered from the local context mapping.

Contig / repliconNZ_AAKB02000001.1Sequence record reported by the local genomic context database.

Genomic interval3 570 686-3 574 279 nt3 594 nt · Reverse (-)

StrandReverse (-)Strand sign follows the local context database convention.

Local TCS group span3 570 686-3 574 898 ntGCF_000167915::NZ_AAKB02000001.1::G00024

Quick actions

Open genome Search genes in genome

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000167915::NZ_AAKB02000001.1::G00024

Graphic view

Compact Biotite-like

Zoom

Full window Focus gene

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.

Contig / repliconNZ_AAKB02000001.1All displayed genes belong to this local TCS context.

Neighborhood span3 570 686-3 574 898 nt4 213 nt

Members21 current focus gene

Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.

3 570 686 nt3 574 898 nt

+-EC53638_RS17965 EC53638_RS17970

Neighborhood gene cards

2 genes in the current local neighborhood.

EC53638_RS17965GCF_000167915#EC53638_RS17965

HKUnorthodoxCurrent focus

3 570 686-3 574 279 nt · Reverse (-)

Old locus Ec53638_3633RefSeq WP_001300674.1

Open current gene

EC53638_RS17970GCF_000167915#EC53638_RS17970

RRunclassified

3 574 284-3 574 898 nt · Reverse (-)

Old locus Ec53638_3634RefSeq WP_000991370.1

Open gene

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Available memberships1 cluster

HKOC_0161042HK

Run 6229 sequencesid 100%cov 80%

PFAM SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt

Current gene is the representative sequence.

Selected clusterHKOC_0161042Run 6 · HK · 229 sequences

Representative sequenceGCF_000167915#EC53638_RS17965The current gene is the representative for this cluster.

PFAM architectureSBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.

Open in cluster search

PFAM architecture for HKOC_0161042

Simplified PFAM architecture for HKOC_0161042

PFAM domain coverage: 802 / 1197 aa (67.0%)

1 aa1197 aa

SBP_bac_3SBP_bac_3HisKAHATPase_cResponse_regHpt

Simplified architecture: SBP_bac_3 + SBP_bac_3 + HisKA + HATPase_c + Response_reg + Hpt
Raw architecture: SBP_bac_3[63-276] | SBP_bac_3[306-520] | HisKA[711-777] | HATPase_c[825-937] | Response_reg[961-1070] | Hpt[1104-1186]
Domain count: 6
Matched identifier: HKOC_0161042
Positioned domains: SBP_bac_3 63-276 ; SBP_bac_3 306-520 ; HisKA 711-777 ; HATPase_c 825-937 ; Response_reg 961-1070 ; Hpt 1104-1186

Cluster members and taxonomy

Representative gene: GCF_000167915#EC53638_RS17965

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 344 610 · GCF_000167915

AssemblyASM16791v2 · Contighaploid

Genome composition5 371 790 bp · 51,0% GCEscherichia coli 53638

Signal transduction countsGenes 62 · HK 29 · RR 33CheA 1 · PP 0

Ranked taxonomy7 ranked levels available

SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia

Lineage path7 lineage nodes

1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Open genome Search genes in genome Search HK genes NCBI assembly files

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