1 PAS#1
98-194 aa · 97 aa · 22.5% of protein
Raw token
PAS:98:0.00000000000238:194:113:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EC53638_RS04565
Histidine kinase, Classic
Escherichia coli 53638 · GCF_000167915
ClassHKTypeClassicLength431 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000167915#EC53638_RS04565Stable P2CS identifier used across views.
GenomeGCF_000167915Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length431 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage275 / 431 aa (63.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa431 aa
Domain-by-domain annotation3 items
2 HisKA#2
203-268 aa · 66 aa · 15.3% of protein
Raw token
HisKA:203:5.6e-20:268:66:643 HATPase_c#3
313-424 aa · 112 aa · 26.0% of protein
Raw token
HATPase_c:313:1.4e-33:424:112:109- Raw architecture: PAS:98:0.00000000000238:194:113:113#HisKA:203:5.6e-20:268:66:64#HATPase_c:313:1.4e-33:424:112:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000167915::NZ_AAKB02000001.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span881459-883501Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEc53638_0902RefSeq proteinWP_000893596.1
Context group ID
GCF_000167915::NZ_AAKB02000001.1::G00008Context members
EC53638_RS04565EC53638_RS04570
Partner locus tags
EC53638_RS04565EC53638_RS04570
Partner old locus tags
Ec53638_0902Ec53638_0903
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000893596.1Primary protein accession used for annex mappings.
UniProt accessionA0A377FCX9Primary UniProt accession resolved in the annex database.
UniProt IDA0A377FCX9_ECOLXDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEC53638_RS04565Primary locus identifier stored in the genes table.
Old locus tagEc53638_0902Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AAKB02000001.1Sequence record reported by the local genomic context database.
Genomic interval881 459-882 754 nt1 296 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span881 459-883 501 ntGCF_000167915::NZ_AAKB02000001.1::G00008
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000167915::NZ_AAKB02000001.1::G00008Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AAKB02000001.1All displayed genes belong to this local TCS context.
Neighborhood span881 459-883 501 nt2 043 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
881 459 nt883 501 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EC53638_RS04565GCF_000167915#EC53638_RS04565
HKClassicCurrent focus
881 459-882 754 nt · Reverse (-)
EC53638_RS04570GCF_000167915#EC53638_RS04570
RROmpR
882 812-883 501 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000167915#EC53638_RS04565The current gene is the representative for this cluster.
PFAM architecturePhoR + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2161410
Simplified PFAM architecture for HKOC_2161410
PFAM domain coverage: 360 / 431 aa (83.5%)
1 aa431 aa
PhoRPASHisKAHATPase_c
- Simplified architecture: PhoR + PAS + HisKA + HATPase_c
- Raw architecture: PhoR[6-91] | PAS[99-194] | HisKA[203-268] | HATPase_c[313-424]
- Domain count: 4
- Matched identifier: HKOC_2161410
- Positioned domains: PhoR 6-91 ; PAS 99-194 ; HisKA 203-268 ; HATPase_c 313-424
Cluster members and taxonomy
Representative gene: GCF_000167915#EC53638_RS04565
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 344 610 · GCF_000167915
AssemblyASM16791v2 · Contighaploid
Genome composition5 371 790 bp · 51,0% GCEscherichia coli 53638
Signal transduction countsGenes 62 · HK 29 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key