Gene detail

EC53638_RS09520

Histidine kinase, Classic

Escherichia coli 53638 · GCF_000167915

ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000167915#EC53638_RS09520Stable P2CS identifier used across views.
GenomeGCF_000167915Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1873510Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_000580431.1 · MIST4 EC53638_RS09520RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
HAMP: 165-234 aa (70 aa)1HisKA: 238-299 aa (62 aa)2HATPase_c: 345-453 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw tokenHAMP:165:0.000000000000938:234:70:69
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw tokenHisKA:238:7.69e-17:299:63:64
3 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw tokenHATPase_c:345:5.67e-30:453:110:109
  • Raw architecture: HAMP:165:0.000000000000938:234:70:69#HisKA:238:7.69e-17:299:63:64#HATPase_c:345:5.67e-30:453:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000167915::NZ_AAKB02000001.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1867167-1869235Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEc53638_1908RefSeq proteinWP_000580431.1
Context group IDGCF_000167915::NZ_AAKB02000001.1::G00014
Context members
EC53638_RS09515EC53638_RS09520
Partner locus tags
EC53638_RS09515EC53638_RS09520
Partner old locus tags
Ec53638_1907Ec53638_1908
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_000580431.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEC53638_RS09520Primary locus identifier stored in the genes table.
Old locus tagEc53638_1908Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AAKB02000001.1Sequence record reported by the local genomic context database.
Genomic interval1 867 862-1 869 235 nt1 374 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 867 167-1 869 235 ntGCF_000167915::NZ_AAKB02000001.1::G00014

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000167915::NZ_AAKB02000001.1::G00014

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AAKB02000001.1All displayed genes belong to this local TCS context.
Neighborhood span1 867 167-1 869 235 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 867 167 nt1 869 235 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EC53638_RS09515GCF_000167915#EC53638_RS09515
RROmpR

1 867 167-1 867 865 nt · Forward (+)

Old locus Ec53638_1907RefSeq WP_001033722.1
EC53638_RS09520GCF_000167915#EC53638_RS09520
HKClassicCurrent focus

1 867 862-1 869 235 nt · Forward (+)

Old locus Ec53638_1908RefSeq WP_000580431.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1873510Run 6 · HK · 1 sequences
Representative sequenceGCF_000167915#EC53638_RS09520The current gene is the representative for this cluster.
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1873510

Simplified PFAM architecture for HKOC_1873510

PFAM domain coverage: 293 / 457 aa (64.1%)

1 aa457 aa
CpxA_peri: 82-150 aaCpxA_periHAMP: 181-233 aaHAMPHisKA: 239-299 aaHisKAHATPase_c: 345-454 aaHATPase_c
CpxA_periHAMPHisKAHATPase_c
  • Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
  • Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
  • Domain count: 4
  • Matched identifier: HKOC_1873510
  • Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Visualization

Representative gene: GCF_000167915#EC53638_RS09520

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 344 610 · GCF_000167915
AssemblyASM16791v2 · Contighaploid
Genome composition5 371 790 bp · 51,0% GCEscherichia coli 53638
Signal transduction countsGenes 62 · HK 29 · RR 33CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key